| Literature DB >> 20687835 |
Mercedes C Becerra1, Sasha C Appleton, Molly F Franke, Katiuska Chalco, Jaime Bayona, Megan B Murray, Carole D Mitnick.
Abstract
We estimated the proportion of recurrence within 2 years among adults cured by individualized multidrug-resistant tuberculosis regimens in Peru. Among 310 individuals with at least 24 months of follow-up, 16 experienced an episode of recurrent tuberculosis. If we assume the worst for treatment effectiveness-that all 16 episodes were caused by the original tuberculosis strain-then 5.2% (95% confidence interval, 3.0%-8.2%) experienced true relapse. This is an upper-bound estimate of relapse on which new regimens must improve.Entities:
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Year: 2010 PMID: 20687835 DOI: 10.1086/655892
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079