Literature DB >> 20685802

The impact of rheumatological evaluation in the management of patients with interstitial lung disease.

Flavia V Castelino1, Hilary Goldberg, Paul F Dellaripa.   

Abstract

OBJECTIVE: We hypothesized that multi-disciplinary assessment of patients with interstitial lung disease (ILD) would lead to improved diagnosis and management.
METHODS: Our multi-disciplinary ILD group evaluated 50 patients referred to our tertiary care practice over a 12-month period. Evaluation consisted of independent assessments by a pulmonologist and rheumatologist, including complete history and physical examination, review of laboratory data, as well as review of imaging and pathological specimens in conjunction with a radiologist and pathologist experienced in ILD. Therapy was initiated or changed in collaboration with the referring physicians.
RESULTS: Mean age was 65 years for patients with rheumatic or CTD-related ILD (CTD-ILD) and 70 years for those with idiopathic pulmonary fibrosis (IPF). The final diagnosis after evaluation in the clinic was 25 patients with CTD-ILD, 15 patients with IPF and 10 patients with other forms of lung disease. Of the patients with a final diagnosis of CTD-ILD, 28% were referred with a diagnosis of IPF. Among those referred with CTD-ILD, 36% had their diagnosis changed to an alternate CTD-ILD. In total, the diagnosis was changed in 54% of patients who presented to the ILD clinic. Changes in therapy occurred in 80% of patients with CTD-ILD and in 27% of patients with IPF.
CONCLUSION: A multi-disciplinary ILD clinic offers patients an innovative mode of health-care delivery that can enhance diagnosis, affect treatment regimens and improve quality of care. Rheumatologists play a significant role in the clinical care of these patients and should evaluate all patients with ILD.

Entities:  

Mesh:

Year:  2010        PMID: 20685802     DOI: 10.1093/rheumatology/keq233

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN: 1462-0324            Impact factor:   7.580


  16 in total

1.  Risk of progression of interstitial pneumonia with autoimmune features to a systemic autoimmune rheumatic disease.

Authors:  Michail K Alevizos; Jon T Giles; Nina M Patel; Elana J Bernstein
Journal:  Rheumatology (Oxford)       Date:  2020-06-01       Impact factor: 7.580

2.  Clinical characteristics and survival in idiopathic pulmonary fibrosis and connective tissue disease-associated usual interstitial pneumonia.

Authors:  Esam H Alhamad
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3.  Impact of an interstitial lung disease service in the diagnosis and management of interstitial lung disease in Singapore.

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Journal:  Singapore Med J       Date:  2019-07-11       Impact factor: 1.858

4.  Clinical significance of serum autoantibodies in idiopathic interstitial pneumonia.

Authors:  Bo Hyoung Kang; Jin Kyeong Park; Jae Hyung Roh; Jin Woo Song; Chang Keun Lee; Miyoung Kim; Se Jin Jang; Thomas V Colby; Dong Soon Kim
Journal:  J Korean Med Sci       Date:  2013-05-02       Impact factor: 2.153

Review 5.  The utility of comprehensive autoantibody testing to differentiate connective tissue disease associated and idiopathic interstitial lung disease subgroup cases.

Authors:  Caroline V Cotton; Lisa G Spencer; Robert P New; Robert G Cooper
Journal:  Rheumatology (Oxford)       Date:  2017-08-01       Impact factor: 7.580

6.  Multidisciplinary management of interstitial lung diseases: A real-life study.

Authors:  Caroline Biglia; Benoît Ghaye; Gregory Reychler; Sandra Koenig; Halil Yildiz; Valérie Lacroix; Farah Tamirou; Delphine Hoton; Thierry Pieters; Antoine Froidure
Journal:  Sarcoidosis Vasc Diffuse Lung Dis       Date:  2019-05-01       Impact factor: 0.670

7.  Pirfenidone treatment of idiopathic pulmonary fibrosis.

Authors:  Ye Gan; Erica L Herzog; Richard H Gomer
Journal:  Ther Clin Risk Manag       Date:  2011-02-08       Impact factor: 2.423

8.  Comparison of characteristics of connective tissue disease-associated interstitial lung diseases, undifferentiated connective tissue disease-associated interstitial lung diseases, and idiopathic pulmonary fibrosis in Chinese Han population: a retrospective study.

Authors:  Lin Pan; Yuan Liu; Rongfei Sun; Mingyu Fan; Guixiu Shi
Journal:  Clin Dev Immunol       Date:  2013-09-19

9.  Interstitial lung disease in suggestive forms of connective tissue disease.

Authors:  Aryeh Fischer
Journal:  J Bras Pneumol       Date:  2013 Nov-Dec       Impact factor: 2.624

10.  Interstitial lung diseases in Saudi Arabia: A single-center study.

Authors:  Esam H Alhamad
Journal:  Ann Thorac Med       Date:  2013-01       Impact factor: 2.219

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