OBJECTIVE: To examine whether gait and postures can accurately be detected with a single small body-fixed device in patients with mild to moderate Parkinson's disease (PD). DESIGN: Results of a triaxial accelerometer-based method were evaluated against video observation scores (criterion measure). Study 1: Subjects performed basic mobility-related activities (walking, lying, sitting, standing) in a fixed and free sequence. Study 2: Subjects were monitored while doing similar activities as in study 1 and while doing usual domestic activities. SETTING: Study 1: Standardized set-up in a movement laboratory. Study 2: Home environment. PARTICIPANTS: (N=37) Study 1: Patients with PD (n=32; mean age +/- SD, 67.3+/-6.6y; mean disease duration +/- SD, 6.1+/-3.4y). Study 2: Patients with PD (n=5; mean age +/- SD, 76.0+/-7.3y; mean disease duration +/- SD, 3.8+/-4.7y). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: The degree of correspondence between the monitor and the video observation for the duration of each activity. Overall agreement, sensitivity, specificity, and positive predictive values were calculated. RESULTS: Study 1: Overall agreement ranged between 69.8% and 90.8% (fixed sequence) and 57.5% and 96.9% (free sequence). Study 2: Overall agreement ranged between 60.0% and 89.2%. Lying, sitting (home), and walking were detected most accurately with mean sensitivity varying from 81.7% to 99.9%. Lower values were found for sitting (laboratory), standing, and shuffling. CONCLUSIONS: This triaxial monitor system is a practical and valuable tool for objective, continuous evaluation of walking and postures in patients with mild to moderate PD. Detection of sitting and standing requires further fine-tuning.
OBJECTIVE: To examine whether gait and postures can accurately be detected with a single small body-fixed device in patients with mild to moderate Parkinson's disease (PD). DESIGN: Results of a triaxial accelerometer-based method were evaluated against video observation scores (criterion measure). Study 1: Subjects performed basic mobility-related activities (walking, lying, sitting, standing) in a fixed and free sequence. Study 2: Subjects were monitored while doing similar activities as in study 1 and while doing usual domestic activities. SETTING: Study 1: Standardized set-up in a movement laboratory. Study 2: Home environment. PARTICIPANTS: (N=37) Study 1: Patients with PD (n=32; mean age +/- SD, 67.3+/-6.6y; mean disease duration +/- SD, 6.1+/-3.4y). Study 2: Patients with PD (n=5; mean age +/- SD, 76.0+/-7.3y; mean disease duration +/- SD, 3.8+/-4.7y). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: The degree of correspondence between the monitor and the video observation for the duration of each activity. Overall agreement, sensitivity, specificity, and positive predictive values were calculated. RESULTS: Study 1: Overall agreement ranged between 69.8% and 90.8% (fixed sequence) and 57.5% and 96.9% (free sequence). Study 2: Overall agreement ranged between 60.0% and 89.2%. Lying, sitting (home), and walking were detected most accurately with mean sensitivity varying from 81.7% to 99.9%. Lower values were found for sitting (laboratory), standing, and shuffling. CONCLUSIONS: This triaxial monitor system is a practical and valuable tool for objective, continuous evaluation of walking and postures in patients with mild to moderate PD. Detection of sitting and standing requires further fine-tuning.
Authors: Rodrigo Cerqueira Borges; Celso R F Carvalho; Alexandra Siqueira Colombo; Mariucha Pereira da Silva Borges; Francisco Garcia Soriano Journal: Intensive Care Med Date: 2015-06-25 Impact factor: 17.440
Authors: Xiaodong Yang; Dou Fan; Aifeng Ren; Nan Zhao; Zhiya Zhang; Daniyal Haider; Muhammad Bilal Khan; Jie Tian Journal: IEEE J Transl Eng Health Med Date: 2019-05-31 Impact factor: 3.316
Authors: Serge H Roy; Bryan T Cole; L Don Gilmore; Carlo J De Luca; Cathi A Thomas; Marie M Saint-Hilaire; S Hamid Nawab Journal: Mov Disord Date: 2013-03-20 Impact factor: 10.338
Authors: Dustin A Heldman; Danielle E Filipkowski; David E Riley; Christina M Whitney; Benjamin L Walter; Steven A Gunzler; Joseph P Giuffrida; Thomas O Mera Journal: Conf Proc IEEE Eng Med Biol Soc Date: 2012