Literature DB >> 20684507

Synthesis of 2,3-dihydroquinazolin-4(1H)-ones by three-component coupling of isatoic anhydride, amines, and aldehydes catalyzed by magnetic Fe(3)O(4) nanoparticles in water.

Zhan-Hui Zhang1, Hong-Yan Lü, Shu-Hong Yang, Jian-Wu Gao.   

Abstract

A simple and efficient protocol for one-pot three-component coupling of isatoic anhydride, amines, and aldehydes in water using magnetically recoverable Fe(3)O(4) nanoparticles is reported. This methodology results in the synthesis of a variety of 2,3-dihydroquinazolin-4(1H)-ones in high yields. The catalyst can be recovered and recycled without a significant loss in the catalytic activity.

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Year:  2010        PMID： 20684507     DOI： 10.1021/cc100047j

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


  8 in total

1.  Aqueous hydrotrope: an efficient and reusable medium for a green one-pot, diversity-oriented synthesis of quinazolinone derivatives.

Authors:  Amol Patil; Madhuri Barge; Gajanan Rashinkar; Rajashri Salunkhe
Journal:  Mol Divers       Date:  2015-03-20       Impact factor: 2.943

2.  Sulfonated magnetic sugarcane bagasse as an efficient natural polymer-based catalyst for the synthesis of nitrogen-containing heterocyclic rings in water.

Authors:  Fahimeh Kazeminava; Ziba Tavakoli
Journal:  Mol Divers       Date:  2022-03-30       Impact factor: 2.943

3.  Magnetically recoverable Fe3O4 nanocatalyst for the synthesis of biodynamically significant 1H-pyrazolo[1,2-b]phthalazine-5,10-diones derivatives and its DFT study.

Authors:  Mohd Danish Ansari; Hozeyfa Sagir; Vijay B Yadav; Neetu Yadav; Ankit Verma; Sonam Shakya; Manjit Singh; I R Siddiqui
Journal:  Mol Divers       Date:  2022-10-07       Impact factor: 3.364

Review 4.  A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen- and oxygen-containing heterocyclic scaffolds.

Authors:  Tejas M Dhameliya; Hiren A Donga; Punit V Vaghela; Bhoomi G Panchal; Dipen K Sureja; Kunjan B Bodiwala; Mahesh T Chhabria
Journal:  RSC Adv       Date:  2020-09-03       Impact factor: 4.036

Review 5.  2,3-Dihydroquinazolin-4(1H)-one as a privileged scaffold in drug design.

Authors:  Mariateresa Badolato; Francesca Aiello; Nouri Neamati
Journal:  RSC Adv       Date:  2018-06-07       Impact factor: 4.036

6.  Photooxidation of 2,3-dihydroquinazolin-4(1H)-ones: retention or elimination of 2-substitution.

Authors:  Hamid Reza Memarian; Reza Aghalar
Journal:  Mol Divers       Date:  2021-01-15       Impact factor: 2.943

7.  β-Cyclodextrin: a supramolecular catalyst for metal-free approach towards the synthesis of 2-amino-4,6-diphenylnicotinonitriles and 2,3-dihydroquinazolin-4(1H)-one.

Authors:  Bijeta Mitra; Gyan Chandra Pariyar; Pranab Ghosh
Journal:  RSC Adv       Date:  2021-01-05       Impact factor: 3.361

8.  Biased multicomponent reactions to develop novel bromodomain inhibitors.

Authors:  Michael R McKeown; Daniel L Shaw; Harry Fu; Shuai Liu; Xiang Xu; Jason J Marineau; Yibo Huang; Xiaofeng Zhang; Dennis L Buckley; Asha Kadam; Zijuan Zhang; Stephen C Blacklow; Jun Qi; Wei Zhang; James E Bradner
Journal:  J Med Chem       Date:  2014-10-31       Impact factor: 7.446
  8 in total

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