OBJECTIVE: To report the authors' experience with laparoscopic ovarian transposition and ovarian function preservation in women who require pelvic irradiation as part of their cancer therapy. DESIGN: Cohort study. SETTING: The gynecologic oncology service in a referral tertiary/quaternary medical center in Saudi Arabia. PATIENTS: Twenty-three premenopausal patients treated with radiotherapy for a pelvic malignancy. INTERVENTIONS: Laparoscopic ovarian transposition to paracolic gutters with uterine conservation. MAIN OUTCOME MEASURES: Preservation of ovarian function assessed by patients' symptoms and serum follicle-stimulating hormone level. RESULTS: Bilateral laparoscopic ovarian transposition was performed in 23 patients: 15 with cervical cancer, 4 with rectal cancer, 3 with Ewing sarcoma, and 1 with Hodgkin lymphoma. No immediate intraoperative or postoperative complications were observed. Three patients were lost to follow-up. Ovarian preservation was achieved in 13 (65%) of 20 patients. Seven patients with low follicle-stimulating hormone levels had regular uterine bleeding at follow-up. CONCLUSIONS: Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure should be considered in all premenopausal women who need to undergo pelvic irradiation as part of their cancer treatment.
OBJECTIVE: To report the authors' experience with laparoscopic ovarian transposition and ovarian function preservation in women who require pelvic irradiation as part of their cancer therapy. DESIGN: Cohort study. SETTING: The gynecologic oncology service in a referral tertiary/quaternary medical center in Saudi Arabia. PATIENTS: Twenty-three premenopausal patients treated with radiotherapy for a pelvic malignancy. INTERVENTIONS: Laparoscopic ovarian transposition to paracolic gutters with uterine conservation. MAIN OUTCOME MEASURES: Preservation of ovarian function assessed by patients' symptoms and serum follicle-stimulating hormone level. RESULTS: Bilateral laparoscopic ovarian transposition was performed in 23 patients: 15 with cervical cancer, 4 with rectal cancer, 3 with Ewing sarcoma, and 1 with Hodgkin lymphoma. No immediate intraoperative or postoperative complications were observed. Three patients were lost to follow-up. Ovarian preservation was achieved in 13 (65%) of 20 patients. Seven patients with low follicle-stimulating hormone levels had regular uterine bleeding at follow-up. CONCLUSIONS: Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure should be considered in all premenopausal women who need to undergo pelvic irradiation as part of their cancer treatment.
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