Literature DB >> 20682811

Misconceptions about gene-environment interactions in psychiatry.

Stanley Zammit1, Michael J Owen, Glyn Lewis.   

Abstract

Misunderstandings surrounding the study of gene-environment interactions are very common. Given the large increase in the number of studies examining interactions in recent years, this raises serious concerns about the value of time and resources spent in these endeavours. In this article we discuss why, despite frequent claims to the contrary, studies of gene-environment interactions are very unlikely to enhance our understanding of disease aetiology or prevention.

Mesh:

Year:  2010        PMID: 20682811     DOI: 10.1136/ebmh.13.3.65

Source DB:  PubMed          Journal:  Evid Based Ment Health        ISSN: 1362-0347


  22 in total

1.  Association between parental hospital-treated infection and the risk of schizophrenia in adolescence and early adulthood.

Authors:  Philip R Nielsen; Thomas M Laursen; Preben B Mortensen
Journal:  Schizophr Bull       Date:  2011-10-20       Impact factor: 9.306

Review 2.  Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia.

Authors:  John J McGrath; Preben Bo Mortensen; Peter M Visscher; Naomi R Wray
Journal:  Schizophr Bull       Date:  2013-08-01       Impact factor: 9.306

3.  Aetiological stratification as a conceptual framework for gene-by-environment interaction research in psychiatry.

Authors:  Ruud van Winkel
Journal:  Epidemiol Psychiatr Sci       Date:  2015-02       Impact factor: 6.892

4.  Genetic variants in 5-HTTLPR, BDNF, HTR1A, COMT, and FKBP5 and risk for treated depression after cancer diagnosis.

Authors:  Nis P Suppli; Jens D Bukh; Terrie E Moffitt; Avshalom Caspi; Christoffer Johansen; Anne Tjønneland; Lars V Kessing; Susanne O Dalton
Journal:  Depress Anxiety       Date:  2017-06-07       Impact factor: 6.505

5.  Brain-derived neurotrophic factor (BDNF) Val66Met and adulthood chronic stress interact to affect depressive symptoms.

Authors:  Rong Jiang; Beverly H Brummett; Michael A Babyak; Ilene C Siegler; Redford B Williams
Journal:  J Psychiatr Res       Date:  2012-11-08       Impact factor: 4.791

Review 6.  Gene × environment interaction models in psychiatric genetics.

Authors:  Katja Karg; Srijan Sen
Journal:  Curr Top Behav Neurosci       Date:  2012

Review 7.  Candidate gene-environment interaction research: reflections and recommendations.

Authors:  Danielle M Dick; Arpana Agrawal; Matthew C Keller; Amy Adkins; Fazil Aliev; Scott Monroe; John K Hewitt; Kenneth S Kendler; Kenneth J Sher
Journal:  Perspect Psychol Sci       Date:  2015-01

8.  A genome-wide association study of depressive symptoms.

Authors:  Karin Hek; Ayse Demirkan; Jari Lahti; Antonio Terracciano; Alexander Teumer; Cornelia M van Duijn; Hans J Grabe; Lenore J Launer; Kathryn L Lunetta; Thomas H Mosley; Anne B Newman; Henning Tiemeier; Joanne Murabito; Marilyn C Cornelis; Najaf Amin; Erin Bakshis; Jens Baumert; Jingzhong Ding; Yongmei Liu; Kristin Marciante; Osorio Meirelles; Michael A Nalls; Yan V Sun; Nicole Vogelzangs; Lei Yu; Stefania Bandinelli; Emelia J Benjamin; David A Bennett; Dorret Boomsma; Alessandra Cannas; Laura H Coker; Eco de Geus; Philip L De Jager; Ana V Diez-Roux; Shaun Purcell; Frank B Hu; Eric B Rimma; David J Hunter; Majken K Jensen; Gary Curhan; Kenneth Rice; Alan D Penman; Jerome I Rotter; Nona Sotoodehnia; Rebecca Emeny; Johan G Eriksson; Denis A Evans; Luigi Ferrucci; Myriam Fornage; Vilmundur Gudnason; Albert Hofman; Thomas Illig; Sharon Kardia; Margaret Kelly-Hayes; Karestan Koenen; Peter Kraft; Maris Kuningas; Joseph M Massaro; David Melzer; Antonella Mulas; Cornelis L Mulder; Anna Murray; Ben A Oostra; Aarno Palotie; Brenda Penninx; Astrid Petersmann; Luke C Pilling; Bruce Psaty; Rajesh Rawal; Eric M Reiman; Andrea Schulz; Joshua M Shulman; Andrew B Singleton; Albert V Smith; Angelina R Sutin; André G Uitterlinden; Henry Völzke; Elisabeth Widen; Kristine Yaffe; Alan B Zonderman; Francesco Cucca; Tamara Harris; Karl-Heinz Ladwig; David J Llewellyn; Katri Räikkönen; Toshiko Tanaka
Journal:  Biol Psychiatry       Date:  2013-01-03       Impact factor: 13.382

9.  Childhood residential mobility, schizophrenia, and bipolar disorder: a population-based study in Denmark.

Authors:  Diana Paksarian; William W Eaton; Preben B Mortensen; Carsten B Pedersen
Journal:  Schizophr Bull       Date:  2014-06-05       Impact factor: 9.306

10.  Kernel Approach for Modeling Interaction Effects in Genetic Association Studies of Complex Quantitative Traits.

Authors:  K Alaine Broadaway; Richard Duncan; Karen N Conneely; Lynn M Almli; Bekh Bradley; Kerry J Ressler; Michael P Epstein
Journal:  Genet Epidemiol       Date:  2015-04-17       Impact factor: 2.135

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.