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Literature DB >> 20680940

Curvularides A-E: antifungal hybrid peptide-polyketides from the endophytic fungus Curvularia geniculata.

Porntep Chomcheon¹, Suthep Wiyakrutta, Thammarat Aree, Nongluksna Sriubolmas, Nattaya Ngamrojanavanich, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop.

Abstract

Five new hybrid peptide-polyketides, curvularides A-E (1-5), were isolated from the endophytic fungus Curvularia geniculata, which was obtained from the limbs of Catunaregam tomentosa. Structure elucidation for curvularides A-E (1-5) was accomplished by analysis of spectroscopic data, as well as by single-crystal X-ray crystallography. Curvularide B (2) exhibited antifungal activity against Candida albicans, and it also showed synergistic activity with a fluconazole drug.

Entities: Chemical Disease Species

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Year: 2010 PMID： 20680940 DOI： 10.1002/chem.201000652

Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236

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Cited

7 in total

1. New aliphatic acid amides from Streptomyces maoxianensis sp. nov.

Authors: Jin-Meng Li; Kai Yan; Hui Zhang; Huan Qi; Ji Zhang; Wen-Sheng Xiang; Ji-Dong Wang; Xiang-Jing Wang
Journal: J Antibiot (Tokyo) Date: 2016-07-27 Impact factor: 2.649

2. Azole-synergistic anti-candidal activity of altenusin, a biphenyl metabolite of the endophytic fungus Alternaria alternata isolated from Terminalia chebula Retz.

Authors: Jatuporn Phaopongthai; Suthep Wiyakrutta; Duangdeun Meksuriyen; Nongluksna Sriubolmas; Khanit Suwanborirux
Journal: J Microbiol Date: 2013-12-19 Impact factor: 3.422

3. Effect of Quinoline on the Phospholipid Profile of Curvularia lunata and Its Microbial Detoxification.

Authors: Aleksandra Felczak; Katarzyna Zawadzka; Przemysław Bernat; Marta Nowak-Lange; Katarzyna Lisowska
Journal: Molecules Date: 2022-03-24 Impact factor: 4.411

4. Polyenylpyrrole derivatives inhibit NLRP3 inflammasome activation and inflammatory mediator expression by reducing reactive oxygen species production and mitogen-activated protein kinase activation.

Authors: Kuo-Feng Hua; Ju-Ching Chou; Yulin Lam; Yu-Ling Tasi; Ann Chen; Shuk-Man Ka; Zhanxiong Fang; May-Lan Liu; Feng-Ling Yang; Yu-Liang Yang; Yi-Chich Chiu; Shih-Hsiung Wu
Journal: PLoS One Date: 2013-10-07 Impact factor: 3.240

Curvularides A-E: antifungal hybrid peptide-polyketides from the endophytic fungus Curvularia geniculata.

1. New aliphatic acid amides from Streptomyces maoxianensis sp. nov.

2. Azole-synergistic anti-candidal activity of altenusin, a biphenyl metabolite of the endophytic fungus Alternaria alternata isolated from Terminalia chebula Retz.

3. Effect of Quinoline on the Phospholipid Profile of Curvularia lunata and Its Microbial Detoxification.

4. Polyenylpyrrole derivatives inhibit NLRP3 inflammasome activation and inflammatory mediator expression by reducing reactive oxygen species production and mitogen-activated protein kinase activation.

5. Phytotoxic and Antifungal Metabolites from Curvularia crepinii QTYC-1 Isolated from the Gut of Pantala flavescens.

6. Cytotoxic and antimicrobial indole alkaloids from an endophytic fungus Chaetomium sp. SYP-F7950 of Panax notoginseng.

7. Endophytes as producers of peptides: an overview about the recently discovered peptides from endophytic microbes.