Literature DB >> 2066096

Subregional localization of the chromosome 21 loci D21S24 and D21S26 using physical mapping techniques.

W Van Hul1, H Backhovens, G Van Camp, P Stinissen, M Cruts, A Wehnert, C Van Broeckhoven.   

Abstract

We were able to refine the chromosomal position of two existing marker loci, using an extended chromosome 21 somatic cell hybrid panel. The locus D21S26 mapped in the region 21q11.2-q21.1, and the locus D21S24 in 21q22.1-q22.2. Physical and genetic analysis indicated that D21S26 is tightly linked to D21S13 and D21S16, two markers previously linked to familial Alzheimer's disease.

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Year:  1991        PMID： 2066096     DOI： 10.1007/BF00204162

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  11 in total

1.  The pericentromeric 21 DNA marker pGSM21 (D21S13) contains an expressed HTF island.

Authors:  P Stinissen; W Van Hul; G Van Camp; H Backhovens; A Wehnert; A Vandenberghe; C Van Broeckhoven
Journal:  Genomics       Date:  1990-05       Impact factor: 5.736

2.  PCR detection of two RFLP's at the D21S13 locus.

Authors:  P Stinissen; A Vandenberghe; C Van Broeckhoven
Journal:  Nucleic Acids Res       Date:  1990-06-25       Impact factor: 16.971

3.  Distribution of meiotic recombination along nondisjunction chromosomes 21 in Down syndrome determined using cytogenetics and RFLP haplotyping.

Authors:  H Meijer; G J Hamers; R J Jongbloed; G P Vaes-Peeters; R R van der Hulst; J P Geraedts
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

4.  Comparative gene mapping of human chromosome 21 and mouse chromosome 16.

Authors:  D R Cox; C J Epstein
Journal:  Ann N Y Acad Sci       Date:  1985       Impact factor: 5.691

5.  Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.

Authors:  P H St George-Hyslop; J L Haines; L A Farrer; R Polinsky; C Van Broeckhoven; A Goate; D R McLachlan; H Orr; A C Bruni; S Sorbi; I Rainero; J F Foncin; D Pollen; J M Cantu; R Tupler; N Voskresenskaya; R Mayeux; J Growden; V A Fried; R H Myers; L Nee; H Backhovens; J J Martin; M Rossor; M J Owen; M Mullan; M E Percy; H Karlinsky; S Rich; L Heston; M Montesi; M Mortilla; N Nacmias; J F Gusella; J A Hardy
Journal:  Nature       Date:  1990-09-13       Impact factor: 49.962

6.  Assignment of the Charcot-Marie-Tooth neuropathy type 1 (CMT 1a) gene to 17p11.2-p12.

Authors:  V Timmerman; P Raeymaekers; P De Jonghe; G De Winter; L Swerts; K Jacobs; J Gheuens; J J Martin; A Vandenberghe; C Van Broeckhoven
Journal:  Am J Hum Genet       Date:  1990-10       Impact factor: 11.025

7.  Genomic sequencing.

Authors:  G M Church; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

8.  Cloned DNA probes regionally mapped to human chromosome 21 and their use in determining the origin of nondisjunction.

Authors:  G D Stewart; P Harris; J Galt; M A Ferguson-Smith
Journal:  Nucleic Acids Res       Date:  1985-06-11       Impact factor: 16.971

9.  Strategies for multilocus linkage analysis in humans.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

10.  Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.

Authors:  K Gardiner; M Horisberger; J Kraus; U Tantravahi; J Korenberg; V Rao; S Reddy; D Patterson
Journal:  EMBO J       Date:  1990-01       Impact factor: 11.598
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