Literature DB >> 20654643

A randomized clinical trial of home-based exercise combined with a slight caloric restriction on obesity prevention among women.

Mauro Felippe Felix Mediano1, José Silvio de Oliveira Barbosa, Aníbal Sanchez Moura, Walter C Willett, Rosely Sichieri.   

Abstract

OBJECTIVE: The study investigated the effectiveness of home-based exercise combined with a slight caloric restriction on weight change during 12 months in non-obese women.
METHODS: A randomized clinical trial with a factorial design was conducted from 2003 to 2005. Two hundred three middle-aged women (Rio de Janeiro/Brazil), 25-45 years, were randomly assigned to one of two groups: control (CG) and home-based exercise (HB). The HB group received a booklet on aerobic exercise that could be practiced at home (3 times/week-40 min/session), in low-moderate intensity, during 12 months. Both groups received dietary counseling aimed at a slight energy restriction of 100-300 calories per day.
RESULTS: The HB experienced a greater weight loss in the first 6 months (-1.4 vs. -0.8 kg; p=0.04), but after 12 months there was no differences between groups (-1.1 vs. -1.0; p=0.20). Of the serum biochemical markers, HDL cholesterol showed major change, with an increase at month 12 of 18.3mg/dl in the HB compared to 9.5 in the CG (p<0.01).
CONCLUSION: Home-based exercise promoted greater weight reduction during the first 6 months after which no further benefits are observed. Continuous favorable changes in HDL cholesterol after 1 year suggest that home-based exercise promote health benefits.
Copyright © 2010 The Institute For Cancer Prevention. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20654643      PMCID: PMC2939161          DOI: 10.1016/j.ypmed.2010.07.012

Source DB:  PubMed          Journal:  Prev Med        ISSN: 0091-7435            Impact factor:   4.018


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