| Literature DB >> 20652012 |
Scott Kellerman1, Shaffiq Essajee.
Abstract
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Year: 2010 PMID: 20652012 PMCID: PMC2907270 DOI: 10.1371/journal.pmed.1000285
Source DB: PubMed Journal: PLoS Med ISSN: 1549-1277 Impact factor: 11.069
Figure 1Number of children under 15 receiving antiretroviral therapy in low- and middle-income countries, 2005–2007.
Source: UNICEF calculations based on data collected through the PMTCT and Paediatric HIV Care and Treatment Report Card process and reported in UNICEF Children and AIDS. 3rd stocktaking report 2008, pp. 34–42 (http://data.unaids.org/pub/Report/2008/20081201_3rd_stocktaking_summary_en.pdf) [20]. Regions were recalculated according to UNICEF classification of regions.
Costs of Pediatric ARV for Resource-Limited Settings, 2009.
| Pediatric Fixed Dose Combination | FDA Approved Date | WHO PQ Date | Cost per Year for a 10kg Child | Per Pack Price |
| D4T/3TC/NVP | ||||
| 6/30/50 | Aug 13 2007 | Apr 23 2008 | $60 | $2.49 (60s) |
| 12/60/100 | $54 | $4.54 (60s) | ||
| D4T/3TC | ||||
| 6/30 | Jun 19 2008 | – | $48 | $2.00 (60s) |
| 12/60 | $41 | $3.42 (60s) | ||
| AZT/3TC/NVP | – | Oct 26 2009 | $108 | $4.50 (60s) |
| AZT/3TC | July 23 2009 | May 25 2009 | $80 | $3.33 (60s) |
| ABC/3TC | Dec 19 2008 | Oct 26 2009 | $180 | $7.50 (60s) |
Based on ref. [21].
Costs based on Clinton Foundation HIV/AIDS Initiative 2009 ceiling prices http://www.clintonfoundation.org/files/chaiarvpricelistaugust2009english.pdf.
Figure 2Despite improvements in PMTCT and infant testing coverage, many women and infants are not tested and are lost to follow up resulting in high infant and child mortality.
Strategies to help increase the identification of infected children depend on the underlying seroprevalence and epidemiology.