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Literature DB >> 20648290

"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site.

Jingwei Xie¹, Xiaoran Li, Justin Lipner, Cionne N Manning, Annie G Schwartz, Stavros Thomopoulos, Younan Xia.

Abstract

We have demonstrated the fabrication of "aligned-to-random" electrospun nanofiber scaffolds that mimic the structural organization of collagen fibers at the tendon-to-bone insertion site. Tendon fibroblasts cultured on such a scaffold exhibited highly organized and haphazardly oriented morphologies, respectively, on the aligned and random portions.

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Year: 2010 PMID： 20648290 PMCID： PMC3609028 DOI： 10.1039/c0nr00192a

Source DB: PubMed Journal: Nanoscale ISSN： 2040-3364 Impact factor: 7.790

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Authors: Thomas J Koob
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7. Putting Electrospun Nanofibers to Work for Biomedical Research.

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5. Bi-material attachment through a compliant interfacial system at the tendon-to-bone insertion site.

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6. Biodegradable electrospun nanofibers coated with platelet-rich plasma for cell adhesion and proliferation.

Authors: Luis Diaz-Gomez; Carmen Alvarez-Lorenzo; Angel Concheiro; Maite Silva; Fernando Dominguez; Faheem A Sheikh; Travis Cantu; Raj Desai; Vanessa L Garcia; Javier Macossay
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7. Fiber stretch and reorientation modulates mesenchymal stem cell morphology and fibrous gene expression on oriented nanofibrous microenvironments.

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