Literature DB >> 20640781

Towards predictive stochastic dynamical modeling of cancer genesis and progression.

P Ao1, D Galas, L Hood, L Yin, X M Zhu.   

Abstract

Based on an innovative endogenous network hypothesis on cancer genesis and progression we have been working towards a quantitative cancer theory along the systems biology perspective. Here we give a brief report on our progress and illustrate that combing ideas from evolutionary and molecular biology, mathematics, engineering, and physics, such quantitative approach is feasible.

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Year:  2010        PMID： 20640781      PMCID： PMC3164764          DOI： 10.1007/s12539-010-0072-3

Source DB:  PubMed          Journal:  Interdiscip Sci        ISSN： 1867-1462            Impact factor:   2.233


  16 in total

1.  Structure of stochastic dynamics near fixed points.

Authors:  Chulan Kwon; Ping Ao; David J Thouless
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-01       Impact factor: 11.205

2.  Positive feedback, stochasticity and genetic competence.

Authors:  Rajesh Karmakar; Indrani Bose
Journal:  Phys Biol       Date:  2007-03-16       Impact factor: 2.583

3.  Reaction coordinates for the flipping of genetic switches.

Authors:  Marco J Morelli; Sorin Tanase-Nicola; Rosalind J Allen; Pieter Rein ten Wolde
Journal:  Biophys J       Date:  2008-01-25       Impact factor: 4.033

Review 4.  Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective.

Authors:  Henry H Q Heng; Steven W Bremer; Joshua B Stevens; Karen J Ye; Guo Liu; Christine J Ye
Journal:  J Cell Physiol       Date:  2009-09       Impact factor: 6.384

5.  Stochastic bifurcation, slow fluctuations, and bistability as an origin of biochemical complexity.

Authors:  Hong Qian; Pei-Zhe Shi; Jianhua Xing
Journal:  Phys Chem Chem Phys       Date:  2009-04-08       Impact factor: 3.676

6.  Systems biology. Attractors and democratic dynamics.

Authors:  Yaneer Bar-Yam; Dion Harmon; Benjamin de Bivort
Journal:  Science       Date:  2009-02-20       Impact factor: 47.728

Review 7.  Spontaneous remission of congenital leukemia.

Authors:  J G Dinulos; D S Hawkins; B S Clark; J S Francis
Journal:  J Pediatr       Date:  1997-08       Impact factor: 4.406

8.  Global view of bionetwork dynamics: adaptive landscape.

Authors:  Ping Ao
Journal:  J Genet Genomics       Date:  2009-02       Impact factor: 4.275

9.  Calculating biological behaviors of epigenetic states in the phage lambda life cycle.

Authors:  X-M Zhu; L Yin; L Hood; P Ao
Journal:  Funct Integr Genomics       Date:  2004-02-05       Impact factor: 3.410

10.  Systems medicine: the future of medical genomics and healthcare.

Authors:  Charles Auffray; Zhu Chen; Leroy Hood
Journal:  Genome Med       Date:  2009-01-20       Impact factor: 11.117
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  10 in total

1.  Endogenous network states predict gain or loss of functions for genetic mutations in hepatocellular carcinoma.

Authors:  Gaowei Wang; Hang Su; Helin Yu; Ruoshi Yuan; Xiaomei Zhu; Ping Ao
Journal:  J R Soc Interface       Date:  2016-02       Impact factor: 4.118

2.  Quantitative implementation of the endogenous molecular-cellular network hypothesis in hepatocellular carcinoma.

Authors:  Gaowei Wang; Xiaomei Zhu; Jianren Gu; Ping Ao
Journal:  Interface Focus       Date:  2014-06-06       Impact factor: 3.906

3.  ACCURATE CHEMICAL MASTER EQUATION SOLUTION USING MULTI-FINITE BUFFERS.

Authors:  Youfang Cao; Anna Terebus; Jie Liang
Journal:  Multiscale Model Simul       Date:  2016-06-29       Impact factor: 1.930

4.  Application of biomarkers in cancer risk management: evaluation from stochastic clonal evolutionary and dynamic system optimization points of view.

Authors:  Xiaohong Li; Patricia L Blount; Thomas L Vaughan; Brian J Reid
Journal:  PLoS Comput Biol       Date:  2011-02-24       Impact factor: 4.475

5.  Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer.

Authors:  Site Li; Xiaomei Zhu; Bingya Liu; Gaowei Wang; Ping Ao
Journal:  Oncotarget       Date:  2015-05-30

6.  LPRP: A Gene-Gene Interaction Network Construction Algorithm and Its Application in Breast Cancer Data Analysis.

Authors:  Lingtao Su; Xiangyu Meng; Qingshan Ma; Tian Bai; Guixia Liu
Journal:  Interdiscip Sci       Date:  2016-09-17       Impact factor: 2.233

Review 7.  What Is Karyotype Coding and Why Is Genomic Topology Important for Cancer and Evolution?

Authors:  Christine J Ye; Lukas Stilgenbauer; Amanda Moy; Guo Liu; Henry H Heng
Journal:  Front Genet       Date:  2019-11-01       Impact factor: 4.599

8.  Key network approach reveals new insight into Alzheimer's disease.

Authors:  Jan K Schluesener; Xiaomei Zhu; Hermann J Schluesener; Gao-Wei Wang; Ping Ao
Journal:  IET Syst Biol       Date:  2014-08       Impact factor: 1.615

Review 9.  Genome Chaos, Information Creation, and Cancer Emergence: Searching for New Frameworks on the 50th Anniversary of the "War on Cancer".

Authors:  Julie Heng; Henry H Heng
Journal:  Genes (Basel)       Date:  2021-12-31       Impact factor: 4.096

Review 10.  Towards the First Principles in Biology and Cancer: New Vistas in Computational Systems Biology of Cancer.

Authors:  Aleš Prokop
Journal:  Life (Basel)       Date:  2021-12-23
  10 in total

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