Literature DB >> 20634311

Transcription: from regulatory ncRNA to incongruent redundancy.

Jane Mellor1.   

Abstract

Transcription is such a fundamental process and has been studied by so many for so long that skeptics might ask what more there is to learn. Those who attended the meeting summarized here on the dynamics of eukaryotic transcription during development were not disappointed. Studying the transcription of genes in stem cells during early development and in model organisms has illuminated mechanisms for transcriptional control that would have been hard to accept even 5 years ago, and consistently challenges the textbook view of transcriptional regulation.

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Year:  2010        PMID: 20634311      PMCID: PMC2904934          DOI: 10.1101/gad.1950310

Source DB:  PubMed          Journal:  Genes Dev        ISSN: 0890-9369            Impact factor:   11.361


  12 in total

1.  Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription.

Authors:  Antonin Morillon; Nickoletta Karabetsou; Anitha Nair; Jane Mellor
Journal:  Mol Cell       Date:  2005-06-10       Impact factor: 17.970

2.  A bivalent chromatin structure marks key developmental genes in embryonic stem cells.

Authors:  Bradley E Bernstein; Tarjei S Mikkelsen; Xiaohui Xie; Michael Kamal; Dana J Huebert; James Cuff; Ben Fry; Alex Meissner; Marius Wernig; Kathrin Plath; Rudolf Jaenisch; Alexandre Wagschal; Robert Feil; Stuart L Schreiber; Eric S Lander
Journal:  Cell       Date:  2006-04-21       Impact factor: 41.582

3.  A chromatin landmark and transcription initiation at most promoters in human cells.

Authors:  Matthew G Guenther; Stuart S Levine; Laurie A Boyer; Rudolf Jaenisch; Richard A Young
Journal:  Cell       Date:  2007-07-13       Impact factor: 41.582

4.  RNA exosome depletion reveals transcription upstream of active human promoters.

Authors:  Pascal Preker; Jesper Nielsen; Susanne Kammler; Søren Lykke-Andersen; Marianne S Christensen; Christophe K Mapendano; Mikkel H Schierup; Torben Heick Jensen
Journal:  Science       Date:  2008-12-04       Impact factor: 47.728

5.  Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters.

Authors:  Leighton J Core; Joshua J Waterfall; John T Lis
Journal:  Science       Date:  2008-12-04       Impact factor: 47.728

6.  The antisense transcriptomes of human cells.

Authors:  Yiping He; Bert Vogelstein; Victor E Velculescu; Nickolas Papadopoulos; Kenneth W Kinzler
Journal:  Science       Date:  2008-12-04       Impact factor: 47.728

7.  Divergent transcription from active promoters.

Authors:  Amy C Seila; J Mauro Calabrese; Stuart S Levine; Gene W Yeo; Peter B Rahl; Ryan A Flynn; Richard A Young; Phillip A Sharp
Journal:  Science       Date:  2008-12-04       Impact factor: 47.728

8.  Molecular basis of RNA-dependent RNA polymerase II activity.

Authors:  Elisabeth Lehmann; Florian Brueckner; Patrick Cramer
Journal:  Nature       Date:  2007-11-15       Impact factor: 49.962

9.  Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

Authors:  Antonin Morillon; Nickoletta Karabetsou; Justin O'Sullivan; Nicholas Kent; Nicholas Proudfoot; Jane Mellor
Journal:  Cell       Date:  2003-11-14       Impact factor: 41.582

10.  Widespread transcription at neuronal activity-regulated enhancers.

Authors:  Tae-Kyung Kim; Martin Hemberg; Jesse M Gray; Allen M Costa; Daniel M Bear; Jing Wu; David A Harmin; Mike Laptewicz; Kellie Barbara-Haley; Scott Kuersten; Eirene Markenscoff-Papadimitriou; Dietmar Kuhl; Haruhiko Bito; Paul F Worley; Gabriel Kreiman; Michael E Greenberg
Journal:  Nature       Date:  2010-04-14       Impact factor: 49.962

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  3 in total

1.  Transcription control by long non-coding RNAs.

Authors:  Tyler Faust; Alan Frankel; Iván D'Orso
Journal:  Transcription       Date:  2012-03-01

2.  Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing.

Authors:  Gaetano Ivan Dellino; Davide Cittaro; Rossana Piccioni; Lucilla Luzi; Stefania Banfi; Simona Segalla; Matteo Cesaroni; Ramiro Mendoza-Maldonado; Mauro Giacca; Pier Giuseppe Pelicci
Journal:  Genome Res       Date:  2012-11-27       Impact factor: 9.043

3.  Acute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression.

Authors:  Olga S Safronova; Ken-Ichi Nakahama; Ikuo Morita
Journal:  Nucleic Acids Res       Date:  2014-07-23       Impact factor: 16.971

  3 in total

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