Literature DB >> 22414755

Transcription control by long non-coding RNAs.

Tyler Faust1, Alan Frankel, Iván D'Orso.   

Abstract

Non-coding RNAs have been found to regulate many cellular processes and thus expand the functional genetic repertoire contained within the genome. With the recent advent of genomic tools, it is now evident that these RNA molecules play central regulatory roles in many transcriptional programs. Here we discuss how they are targeted to promoters in several cases and how they operate at specific points in the transcription cycle to precisely control gene expression.

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Year:  2012        PMID: 22414755      PMCID: PMC3337829          DOI: 10.4161/trns.19349

Source DB:  PubMed          Journal:  Transcription        ISSN: 2154-1272


  97 in total

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9.  Characterization of the structure, function, and mechanism of B2 RNA, an ncRNA repressor of RNA polymerase II transcription.

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2.  Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.

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