| Literature DB >> 20631733 |
Abstract
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is a pleiotropic cascade essential to cytokine and growth hormone receptor signaling. Signaling through the JAK/STAT pathway is important for the kidney's response to injury in disease. Pang et al. confirm that activation of STAT3 mediates renal fibrosis in the unilateral ureteral obstruction experimental model.Entities:
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Year: 2010 PMID: 20631733 DOI: 10.1038/ki.2010.158
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612