Literature DB >> 20621679

High prevalence of pancreatic cysts detected by screening magnetic resonance imaging examinations.

Koen de Jong1, C Yung Nio, John J Hermans, Marcel G Dijkgraaf, Dirk J Gouma, Casper H J van Eijck, Eddy van Heel, Gunter Klass, Paul Fockens, Marco J Bruno.   

Abstract

BACKGROUND & AIMS: The prevalence of pancreatic cysts is not known, but asymptomatic pancreatic cysts are diagnosed with increasing frequency. We investigated the prevalence of pancreatic cysts in individuals who were screened by magnetic resonance imaging (MRI) as part of a preventive medical examination.
METHODS: Data from consecutive persons who underwent abdominal MRI (n = 2803; 1821 men; mean age, 51.1 +/- 10.8 y) at an institute of preventive medical care were included from a prospective database. All individuals had completed an application form including questions about possible abdominal complaints and prior surgery. MRI reports were reviewed for the presence of pancreatic cysts. Original image sets of all positive MRI reports and a representative sample of the negative series were re-assessed by a blinded, independent radiologist.
RESULTS: Pancreatic cysts were reported in 66 persons (2.4%; 95% confidence interval, 1.9-3.0); prevalence correlated with increasing age (P < .001). There was no difference in prevalence between sexes (P = .769). There was no correlation between abdominal complaints and the presence of pancreatic cysts (P = .542). Four cysts (6%) were larger than 2 cm and 3 (5%) were larger than 3 cm. Review of the original image sets by the independent radiologist did not significantly change these findings.
CONCLUSIONS: The prevalence of pancreatic cysts in a large consecutive series of individuals who underwent an MRI at a preventive medical examination was 2.4%. Prevalence increased with age, but did not differ between sexes. Only a minority of cysts were larger than 2 cm. Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20621679     DOI: 10.1016/j.cgh.2010.05.017

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN: 1542-3565            Impact factor:   11.382


  145 in total

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Review 4.  [Surgical therapy of intraductal papillary mucinous neoplasms of the pancreas].

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5.  Operative resection is currently overutilized for cystic lesions of the pancreas.

Authors:  Peter J Allen
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Review 6.  Novel Biomarkers for Pancreatic Cysts.

Authors:  Harkirat Singh; Kevin McGrath; Aatur D Singhi
Journal:  Dig Dis Sci       Date:  2017-02-14       Impact factor: 3.199

7.  Natural History of Patients Followed Radiographically with Mucinous Cysts of the Pancreas.

Authors:  Linda M Pak; Michael I D'Angelica; Ronald P DeMatteo; T Peter Kingham; Vinod P Balachandran; William R Jarnagin; Peter J Allen
Journal:  J Gastrointest Surg       Date:  2017-05-17       Impact factor: 3.452

8.  KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound.

Authors:  James R Eshleman; Alexis L Norris; Yoshihiko Sadakari; Marija Debeljak; Michael Borges; Colleen Harrington; Elaine Lin; Aaron Brant; Thomas Barkley; J Alejandro Almario; Mark Topazian; James Farrell; Sapna Syngal; Jeffrey H Lee; Jun Yu; Ralph H Hruban; Mitsuro Kanda; Marcia Irene Canto; Michael Goggins
Journal:  Clin Gastroenterol Hepatol       Date:  2014-12-04       Impact factor: 11.382

9.  Pancreatic cyst prevalence and the risk of mucin-producing adenocarcinoma in US adults.

Authors:  Timothy B Gardner; Lisa M Glass; Kerrington D Smith; Gregory H Ripple; Richard J Barth; David A Klibansky; Thomas A Colacchio; Michael J Tsapakos; Arief A Suriawinata; Gregory J Tsongalis; J Marc Pipas; Stuart R Gordon
Journal:  Am J Gastroenterol       Date:  2013-10       Impact factor: 10.864

Review 10.  Cyst Fluid Biomarkers - Diagnosis and Prediction of Malignancy for Cystic Lesions of the Pancreas.

Authors:  Aadhithya Raman; Anne Marie Lennon
Journal:  Visc Med       Date:  2018-06-13
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