Literature DB >> 2062117

The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats.

C P Montoya1, L J Campbell-Hope, K D Pemberton, S B Dunnett.   

Abstract

A novel reaching test for the rat has been developed to assess the independent use of forelimbs in skilled reaching and grasping tasks. The apparatus is a plexiglas box with a removable baited double staircase. Food pellets are placed on the staircase and presented bilaterally at 7 graded stages of reaching difficulty to provide objective measures of side bias, maximum forelimb extension and grasping skill. In the present experiment, the apparatus was used to assess the reaching performance of rats following unilateral lesions of the sensorimotor cortex, unilateral lesions of the posterior cortex or bilateral lesions of the olfactory bulbs. The task has the advantage of objective over rating measurement, and the simplicity of the apparatus permits many animals to be tested concurrently.

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Year:  1991        PMID: 2062117     DOI: 10.1016/0165-0270(91)90048-5

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  127 in total

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2.  Functional assessments in the rodent stroke model.

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Review 3.  Behavioral testing in animal models of spinal cord injury.

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6.  An automated behavioral box to assess forelimb function in rats.

Authors:  Chelsea C Wong; Dhakshin S Ramanathan; Tanuj Gulati; Seok Joon Won; Karunesh Ganguly
Journal:  J Neurosci Methods       Date:  2015-03-10       Impact factor: 2.390

Review 7.  Functional magnetic resonance imaging in chronic ischaemic stroke.

Authors:  Evelyn M R Lake; Paolo Bazzigaluppi; Bojana Stefanovic
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2016-10-05       Impact factor: 6.237

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Authors:  Patricia Vergara-Aragon; Claudia L R Gonzalez; Ian Q Whishaw
Journal:  J Neurosci       Date:  2003-01-15       Impact factor: 6.167

9.  Implications of poly(N-isopropylacrylamide)-g-poly(ethylene glycol) with codissolved brain-derived neurotrophic factor injectable scaffold on motor function recovery rate following cervical dorsolateral funiculotomy in the rat.

Authors:  Lauren Conova Grous; Jennifer Vernengo; Ying Jin; B Timothy Himes; Jed S Shumsky; Itzhak Fischer; Anthony Lowman
Journal:  J Neurosurg Spine       Date:  2013-04-12

Review 10.  Use of magnetic resonance imaging to predict outcome after stroke: a review of experimental and clinical evidence.

Authors:  Tracy D Farr; Susanne Wegener
Journal:  J Cereb Blood Flow Metab       Date:  2010-01-20       Impact factor: 6.200

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