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Literature DB >> 2061095

Effects of population structure on DNA fingerprint analysis in forensic science.

Abstract

DNA fingerprints are used in forensic sciences to identify individuals. However, current analyses could underestimate the probability of two individuals sharing the same profile because the effect of population structure is not incorporated. An alternative analysis is proposed to take into account population stratification. The analysis uses studies of inbreeding in human populations to obtain an empirical upper bound on the magnitude of the effect.

Entities: Species

Mesh：

Year: 1991 PMID： 2061095 DOI： 10.1038/hdy.1991.37

Source DB: PubMed Journal: Heredity (Edinb) ISSN： 0018-067X Impact factor: 3.821

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Cited

11 in total

1. Independence of VNTR alleles defined as fixed bins.

Authors: B S Weir
Journal: Genetics Date: 1992-04 Impact factor: 4.562

2. Population genetics of STR loci in Caucasians.

Authors: D J Balding; M Greenhalgh; R A Nichols
Journal: Int J Legal Med Date: 1996 Impact factor: 2.686

3. Statistical analysis of a large file of data from STR profiles of British Caucasians to support forensic casework.

Authors: I W Evett; J A Lambert; J S Buckleton; B S Weir
Journal: Int J Legal Med Date: 1996 Impact factor: 2.686

4. The effect of relatedness on likelihood ratios and the use of conservative estimates.

Authors: J F Brookfield
Journal: Genetica Date: 1995 Impact factor: 1.082

5. A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity.

Authors: D J Balding; R A Nichols
Journal: Genetica Date: 1995 Impact factor: 1.082

Effects of population structure on DNA fingerprint analysis in forensic science.

1. Independence of VNTR alleles defined as fixed bins.

2. Population genetics of STR loci in Caucasians.

3. Statistical analysis of a large file of data from STR profiles of British Caucasians to support forensic casework.

4. The effect of relatedness on likelihood ratios and the use of conservative estimates.

5. A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity.

6. Population genetics of short tandem repeat (STR) loci.

7. Exact tests for association between alleles at arbitrary numbers of loci.

8. The effects of inbreeding on DNA profile frequency estimates using PCR-based loci.

9. Kinship bioassay on hypervariable loci in blacks and Caucasians.

10. Establishing the robustness of short-tandem-repeat statistics for forensic applications.