Literature DB >> 20606777

Anti-allergic, anti-pruritic, and anti-inflammatory activities of Centella asiatica extracts.

Mathew George1, Lincy Joseph.   

Abstract

This study investigated antipruritic and anti-inflammatory effect of Centella asiatica extract in rats and anti-allergic in vitro using sheep (Capra hircus) serum method and compound 48/80 induced mast cell degranulation method, compared with standard drug ketotifen fumarate. In rats, extract of Centella asiatica administered orally was examined for anti-pruritic study and chlorpheniramine maleate was used as standard drug while carageenan paw induced inflammatory method was used for the antiinfammatory study. The results show that the extracts of Centella asiatica exhibited antiallergic, anti-pruritic and anti-inflammatory activities.

Entities:  

Keywords:  Anti-allergic; Anti-inflammatory; Anti-pruritic; Centella asiatica extract

Mesh：

Substances：

Year:  2009        PMID： 20606777      PMCID： PMC2816466          DOI： 10.4314/ajtcam.v6i4.57206

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN： 2505-0044


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