Literature DB >> 20600689

Evidences of osteoporosis improvement in Wistar rats treated with Ginkgo biloba extract: a histomorphometric study of mandible and femur.

L M F Lucinda1, B J Vieira, T T Oliveira, R C S Sá, V M Peters, J E P Reis, M O Guerra.   

Abstract

This study was aimed at investigating the anti-osteoporotic effects of the extract of Ginkgo biloba (EGb) in glucocorticoid-induced-osteoporosis. A significant reduction was observed in the percentage of the bone of the osteoporosis group in both the mandible and femur. The EGb group treated with 28 and 56 mg/Kg showed a significant increase in the percentage of trabecular bone (PTB) of the femur. The percentage of the alveolar bone of the mandible (PAB) had a significant increase with all doses of EGb. The treatment with EGb significantly reversed the loss of the PAB of the mandible and of the PTB of the femur.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 20600689     DOI： 10.1016/j.fitote.2010.06.014

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


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