| Literature DB >> 20598377 |
Sandra Nischwitz1, Sabine Cepok, Antje Kroner, Christiane Wolf, Matthias Knop, Felix Müller-Sarnowski, Hildegard Pfister, Darina Roeske, Peter Rieckmann, Bernhard Hemmer, Marcus Ising, Manfred Uhr, Thomas Bettecken, Florian Holsboer, Bertram Müller-Myhsok, Frank Weber.
Abstract
In a genome wide association study consisting of 592 German multiple sclerosis (MS) patients and 825 controls we were able to replicate the association of the HLA region with MS independently of previous case control studies. No SNPs outside the HLA region reached a genome wide level of significance. Nevertheless, we found suggestive evidence for an association of MS with variants in two new genes, the VAV2 gene and the gene for ZNF433.Entities:
Mesh：
Substances：
Year: 2010 PMID： 20598377 DOI： 10.1016/j.jneuroim.2010.06.003
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478