Literature DB >> 20595912

Exposure error masks the relationship between traffic-related air pollution and heart rate variability.

Helen H Suh1, Antonella Zanobetti.   

Abstract

OBJECTIVE: We examined whether more precise exposure measures would better detect associations between traffic-related pollution, elemental carbon (EC), nitrogen dioxide (NO2), and heart rate variability (HRV).
METHODS: Repeated 24-hour personal and ambient PM2.5, EC, and NO2 were measured for 30 people living in Atlanta, GA. The association between HRV and either ambient concentrations or personal exposures was examined using linear mixed effects models.
RESULTS: Ambient PM2.5, EC, NO2, and personal PM2.5 were not associated with HRV. Personal EC and NO2 measured 24 hours before HRV were associated with decreased RMSSD, PNN50, and HF and with increased LF/HF. RMSSD decreased by 10.97% (95% confidence interval: -18.00 to -3.34) for an inter-quartile range change in personal EC (0.81 microg/m3).
CONCLUSIONS: Results indicate decreased vagal tone in response to traffic pollutants, which can best be detected with precise personal exposure measures.

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Year:  2010        PMID: 20595912      PMCID: PMC2911027          DOI: 10.1097/JOM.0b013e3181e8071f

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN: 1076-2752            Impact factor:   2.162


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