Literature DB >> 20585823

Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor.

A Halevy1, I Samuk, Z Halpern, L Copel, J Sandbank, Y Ziv.   

Abstract

We report the case of a patient who developed a desmoid tumor following total proctocolectomy and J-pouch reconstruction that was unresponsive to any medical treatment. Based on estrogen receptor alpha (ERalpha) and progesterone receptor (PR) evaluation (ERalpha-negative, but PR-positive), treatment with mifepristone, a pure antiprogesterone drug, was initiated, and partial tumor regression was achieved.

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Year:  2010        PMID： 20585823     DOI： 10.1007/s10151-010-0591-2

Source DB:  PubMed          Journal:  Tech Coloproctol        ISSN： 1123-6337            Impact factor:   3.781


  15 in total

1.  Desmoid disease as a part of familial adenomatous polyposis coli.

Authors:  H J Järvinen
Journal:  Acta Chir Scand       Date:  1987

2.  Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone.

Authors:  S M Grunberg; M H Weiss; I M Spitz; J Ahmadi; A Sadun; C A Russell; L Lucci; L L Stevenson
Journal:  J Neurosurg       Date:  1991-06       Impact factor: 5.115

3.  Intestinal transplant for recurring mesenteric desmoid tumour.

Authors:  R Y Calne; S G Pollard; N V Jamieson; P J Friend; A Rasmussen; G Neale; D G Wight; V Joysey; E P Wraight
Journal:  Lancet       Date:  1993-07-03       Impact factor: 79.321

Review 4.  Desmoids in familial adenomatous polyposis.

Authors:  S K Clark; R K Phillips
Journal:  Br J Surg       Date:  1996-11       Impact factor: 6.939

5.  Contragestion and other clinical applications of RU 486, an antiprogesterone at the receptor.

Authors:  E E Baulieu
Journal:  Science       Date:  1989-09-22       Impact factor: 47.728

6.  Intestinal transplantation for the treatment of desmoid tumors associated with familial adenomatous polyposis.

Authors:  M A Chatzipetrou; A G Tzakis; A D Pinna; T Kato; E P Misiakos; A K Tsaroucha; D Weppler; P Ruiz; M Berho; T Fishbein; H O Conn; C Ricordi
Journal:  Surgery       Date:  2001-03       Impact factor: 3.982

7.  Pharmacologic treatment of desmoid tumors in familial adenomatous polyposis: results of an in vitro study.

Authors:  F Tonelli; R Valanzano; M L Brandi
Journal:  Surgery       Date:  1994-04       Impact factor: 3.982

Review 8.  Desmoid tumour in familial adenomatous polyposis. A review of literature.

Authors:  A L Knudsen; S Bülow
Journal:  Fam Cancer       Date:  2001       Impact factor: 2.375

9.  Desmoid tumours in familial adenomatous polyposis.

Authors:  A K Gurbuz; F M Giardiello; G M Petersen; A J Krush; G J Offerhaus; S V Booker; M C Kerr; S R Hamilton
Journal:  Gut       Date:  1994-03       Impact factor: 23.059

10.  Antiangiogenic treatment of mesenteric desmoid tumors with toremifene and interferon alfa-2b: report of two cases.

Authors:  Jan Heidemann; Hitoshi Ogawa; Mary F Otterson; Vinod B Shidham; David G Binion
Journal:  Dis Colon Rectum       Date:  2004-01-14       Impact factor: 4.585
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  1 in total

1.  Mesenteric Fibromatosis in Crohn's Disease as a Potential Effect of Adalimumab.

Authors:  Abdelhai Abdelqader; Aditya Goud; Albert S Fleisher
Journal:  ACG Case Rep J       Date:  2016-04-15
  1 in total

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