Literature DB >> 20574566

Asymmetric total synthesis of ent-heliespirones A & C.

Chong Huang1, Bo Liu.   

Abstract

A concise 8-step synthetic route toward ent-heliespirones A & C is described. This synthetic strategy features a highly diastereoselective palladium-catalyzed Michael addition to form 3,5-trans lactone and a final biomimetic intramolecular oxa-spirocyclization.

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Year:  2010        PMID： 20574566     DOI： 10.1039/c0cc00481b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Structural determination of complex natural products by quantum mechanical calculations of (13)C NMR chemical shifts: development of a parameterized protocol for terpenes.

Authors:  Ana Carolina Ferreira de Albuquerque; Daniel Joras Ribeiro; Mauro Barbosa de Amorim
Journal:  J Mol Model       Date:  2016-07-16       Impact factor: 1.810

2.  Mechanism-based enhancement of scope and enantioselectivity for reactions involving a copper-substituted stereogenic carbon centre.

Authors:  Jaehee Lee; Suttipol Radomkit; Sebastian Torker; Juan Del Pozo; Amir H Hoveyda
Journal:  Nat Chem       Date:  2017-10-02       Impact factor: 24.427

3.  Elucidation of the regio- and chemoselectivity of enzymatic allylic oxidations with Pleurotus sapidus - conversion of selected spirocyclic terpenoids and computational analysis.

Authors:  Verena Weidmann; Mathias Schaffrath; Holger Zorn; Julia Rehbein; Wolfgang Maison
Journal:  Beilstein J Org Chem       Date:  2013-10-29       Impact factor: 2.883

4.  A broadly applicable NHC-Cu-catalyzed approach for efficient, site-, and enantioselective coupling of readily accessible (pinacolato)alkenylboron compounds to allylic phosphates and applications to natural product synthesis.

Authors:  Fang Gao; James L Carr; Amir H Hoveyda
Journal:  J Am Chem Soc       Date:  2014-01-28       Impact factor: 15.419
  4 in total

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