Literature DB >> 20571136

Successful subject recruitment for a prostate cancer behavioral intervention trial.

Sue P Heiney1, Swann Arp Adams, Bettina F Drake, Lisa H Bryant, Lynne Bridges, James R Hebert.   

Abstract

BACKGROUND: Inadequate participant recruitment, which may lead to unrepresentative study samples that threaten a study's validity, is often a major challenge in the conduct of research studies.
PURPOSE: The purpose of this article is to describe the development and implementation of a recruitment plan and evaluate the different recruitment strategies for a prostate cancer behavioral intervention trial.
METHODS: Our recruitment plan was based on a framework (The Heiney-Adams Recruitment Model) that we developed, which combines relationship building and social marketing. We evaluated the success of our model using several different recruitment sources including: mailed letters, physician referral, and self-referral.
RESULTS: Recruitment rates ranged from 67% for a support services department mailing to 100% for physician referral. While our original list of contacted patients was comprised of only 13% African American (AA) men, 22% of our recruited participants were AA. LIMITATIONS: One of the strongest barriers to recruitment was strict patient eligibility. Another significant barrier was the lack of electronic records systems to allow for the identification of large numbers of potential participants.
CONCLUSIONS: In conclusion, our model incorporating social marketing and relationship building was quite successful in recruiting for a prostate cancer behavioral study, particularly AA participants. In developing strategies, future researchers should attend to issues of staffing, financial resources, physician support, and eligibility criteria in the light of study accrual.

Entities:  

Mesh:

Year:  2010        PMID: 20571136      PMCID: PMC2959175          DOI: 10.1177/1740774510373491

Source DB:  PubMed          Journal:  Clin Trials        ISSN: 1740-7745            Impact factor:   2.486


  12 in total

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3.  Evaluation of conceptual framework for recruitment of African American patients with breast cancer.

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Review 6.  Prostate cancer disparities in South Carolina: early detection, special programs, and descriptive epidemiology.

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  9 in total

1.  Evaluation of conceptual framework for recruitment of African American patients with breast cancer.

Authors:  Sue P Heiney; Swann Arp Adams; Linda M Wells; Hiluv Johnson
Journal:  Oncol Nurs Forum       Date:  2010-05       Impact factor: 2.172

2.  Impact of a clinical trial initiative on clinical trial enrollment in a multidisciplinary prostate cancer clinic.

Authors:  Lydia T Madsen; Deborah A Kuban; Seungtaek Choi; John W Davis; Jeri Kim; Andrew K Lee; Delora Domain; Larry Levy; Louis L Pisters; Curtis A Pettaway; John F Ward; Christopher Logothetis; Karen E Hoffman
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3.  Feasibility of feature-based indexing, clustering, and search of clinical trials. A case study of breast cancer trials from ClinicalTrials.gov.

Authors:  M R Boland; R Miotto; J Gao; C Weng
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4.  African American men's and women's perceptions of clinical trials research: focusing on prostate cancer among a high-risk population in the South.

Authors:  Otis L Owens; Dawnyéa D Jackson; Tracey L Thomas; Daniela B Friedman; James R Hébert
Journal:  J Health Care Poor Underserved       Date:  2013-11

Review 5.  Strategies to improve recruitment to randomised trials.

Authors:  Shaun Treweek; Marie Pitkethly; Jonathan Cook; Cynthia Fraser; Elizabeth Mitchell; Frank Sullivan; Catherine Jackson; Tyna K Taskila; Heidi Gardner
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7.  Recruitment strategies in randomised controlled trials of men aged 50 years and older: a systematic review.

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8.  Cost analysis and efficacy of recruitment strategies used in a large pragmatic community-based clinical trial targeting low-income seniors: a comparative descriptive analysis.

Authors:  Sravya Kakumanu; Braden J Manns; Sophia Tran; Terry Saunders-Smith; Brenda R Hemmelgarn; Marcello Tonelli; Ross Tsuyuki; Noah Ivers; Danielle Southern; Jeff Bakal; David J T Campbell
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9.  Using marketing theory to inform strategies for recruitment: a recruitment optimisation model and the txt2stop experience.

Authors:  Leandro Galli; Rosemary Knight; Steven Robertson; Elizabeth Hoile; Olubukola Oladapo; David Francis; Caroline Free
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