Literature DB >> 20566773

Synergistic activities of an efflux pump inhibitor and iron chelators against Pseudomonas aeruginosa growth and biofilm formation.

Yang Liu1, Liang Yang, Søren Molin.   

Abstract

The efflux pump inhibitor phenyl-arginine-beta-naphthylamide (PAbetaN) was paired with iron chelators 2,2'-dipyridyl, acetohydroxamic acid, and EDTA to assess synergistic activities against Pseudomonas aeruginosa growth and biofilm formation. All of the tested iron chelators synergistically inhibited P. aeruginosa growth and biofilm formation with PAbetaN. PAbetaN-EDTA showed the most promising activity against P. aeruginosa growth and biofilm formation.

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Year:  2010        PMID： 20566773      PMCID： PMC2935009          DOI： 10.1128/AAC.00463-10

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

1.  Expression of the multidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression.

Authors:  K Poole; K Tetro; Q Zhao; S Neshat; D E Heinrichs; N Bianco
Journal:  Antimicrob Agents Chemother       Date:  1996-09       Impact factor: 5.191

Review 2.  Genome organization in Pseudomonas.

Authors:  B W Holloway; A F Morgan
Journal:  Annu Rev Microbiol       Date:  1986       Impact factor: 15.500

3.  Release of lipopolysaccharide by EDTA treatment of E. coli.

Authors:  L Leive
Journal:  Biochem Biophys Res Commun       Date:  1965-11-22       Impact factor: 3.575

4.  Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy.

Authors:  O Lomovskaya; M S Warren; A Lee; J Galazzo; R Fronko; M Lee; J Blais; D Cho; S Chamberland; T Renau; R Leger; S Hecker; W Watkins; K Hoshino; H Ishida; V J Lee
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

Review 5.  Multidrug efflux in Pseudomonas aeruginosa: components, mechanisms and clinical significance.

Authors:  K Poole; R Srikumar
Journal:  Curr Top Med Chem       Date:  2001-05       Impact factor: 3.295

6.  Cloning and sequence analysis of an EnvCD homologue in Pseudomonas aeruginosa: regulation by iron and possible involvement in the secretion of the siderophore pyoverdine.

Authors:  K Poole; D E Heinrichs; S Neshat
Journal:  Mol Microbiol       Date:  1993-11       Impact factor: 3.501

7.  Pyoverdine and PQS mediated subpopulation interactions involved in Pseudomonas aeruginosa biofilm formation.

Authors:  Liang Yang; Martin Nilsson; Morten Gjermansen; Michael Givskov; Tim Tolker-Nielsen
Journal:  Mol Microbiol       Date:  2009-11-02       Impact factor: 3.501

8.  Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon.

Authors:  K Poole; K Krebes; C McNally; S Neshat
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490

Review 9.  Infections caused by Pseudomonas aeruginosa.

Authors:  G P Bodey; R Bolivar; V Fainstein; L Jadeja
Journal:  Rev Infect Dis       Date:  1983 Mar-Apr

10.  Role of autolysins in the EDTA-induced lysis of Pseudomonas aeruginosa.

Authors:  S R Watt; A J Clarke
Journal:  FEMS Microbiol Lett       Date:  1994-11-15       Impact factor: 2.742
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  23 in total

1.  Biofilm formation by otopathogenic strains of Pseudomonas aeruginosa is not consistently inhibited by ethylenediaminetetraacetic acid.

Authors:  Joseph Zenga; Patricia M Gagnon; Joseph Vogel; Richard A Chole
Journal:  Otol Neurotol       Date:  2012-08       Impact factor: 2.311

Review 2.  Applying insights from biofilm biology to drug development - can a new approach be developed?

Authors:  Thomas Bjarnsholt; Oana Ciofu; Søren Molin; Michael Givskov; Niels Høiby
Journal:  Nat Rev Drug Discov       Date:  2013-10       Impact factor: 84.694

Review 3.  The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Authors:  Xian-Zhi Li; Patrick Plésiat; Hiroshi Nikaido
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

4.  Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms.

Authors:  Wang Hengzhuang; Hong Wu; Oana Ciofu; Zhijun Song; Niels Høiby
Journal:  Antimicrob Agents Chemother       Date:  2011-06-13       Impact factor: 5.191

Review 5.  The hydrophobic trap-the Achilles heel of RND efflux pumps.

Authors:  Zachary Aron; Timothy J Opperman
Journal:  Res Microbiol       Date:  2017-11-13       Impact factor: 3.992

6.  Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database.

Authors:  Sean Yang-Yi Tan; Song-Lin Chua; Yicai Chen; Scott A Rice; Staffan Kjelleberg; Thomas E Nielsen; Liang Yang; Michael Givskov
Journal:  Antimicrob Agents Chemother       Date:  2013-09-03       Impact factor: 5.191

7.  Ecology drives the evolution of diverse social strategies in Pseudomonas aeruginosa.

Authors:  Alexandre R T Figueiredo; Andreas Wagner; Rolf Kümmerli
Journal:  Mol Ecol       Date:  2021-08-28       Impact factor: 6.622

8.  Bis-(3'-5')-cyclic dimeric GMP regulates antimicrobial peptide resistance in Pseudomonas aeruginosa.

Authors:  Song Lin Chua; Sean Yang-Yi Tan; Morten Theil Rybtke; Yicai Chen; Scott A Rice; Staffan Kjelleberg; Tim Tolker-Nielsen; Liang Yang; Michael Givskov
Journal:  Antimicrob Agents Chemother       Date:  2013-02-12       Impact factor: 5.191

9.  Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data.

Authors:  Lei Yang; Martin Holm Rau; Liang Yang; Niels Høiby; Søren Molin; Lars Jelsbak
Journal:  BMC Microbiol       Date:  2011-08-18       Impact factor: 3.605

10.  Production, characterization and bio-emulsifying application of exopolysaccharides from Rhodotorula mucilaginosa YMM19.

Authors:  Youssef M M Mohammed; Mona M G Saad; Samir A M Abdelgaleil
Journal:  3 Biotech       Date:  2021-06-21       Impact factor: 2.893
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