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Literature DB >> 20559981

Implantable device therapy for the treatment of resistant hypertension.

Nikhil Joshi¹, Jeremy Taylor, John D Bisognano.

Abstract

The prevalence of resistant hypertension continues to increase and the standard approaches of therapeutic lifestyle changes and drug therapy are ineffective in bringing many of these patients to goal blood pressure. Electrical stimulation of the carotid sinus baroreceptor through a surgically implanted device is presently under clinical investigation and is showing some encouraging early results. This review discusses the evolution of this therapy including a review of the current data available from the early stages of ongoing clinical trials.

Entities: Disease Species

Mesh：

Substances：
Antihypertensive Agents

Year: 2009 PMID： 20559981 DOI： 10.1007/s12265-009-9093-x

Source DB: PubMed Journal: J Cardiovasc Transl Res ISSN： 1937-5387 Impact factor: 4.132

19 in total

1. Baroceptor function in chronic renal hypertension.

Authors: J W MCCUBBIN; J H GREEN; I H PAGE
Journal: Circ Res Date: 1956-03 Impact factor: 17.367

2. Influence of prolonged baroreflex activation on arterial pressure in angiotensin hypertension.

Authors: Thomas E Lohmeier; Terry M Dwyer; Drew A Hildebrandt; Eric D Irwin; Martin A Rossing; David J Serdar; Robert S Kieval
Journal: Hypertension Date: 2005-10-10 Impact factor: 10.190

3. An implantable carotid sinus stimulator for drug-resistant hypertension: surgical technique and short-term outcome from the multicenter phase II Rheos feasibility trial.

Authors: Karl A Illig; Mark Levy; Luis Sanchez; Gregory D Trachiotis; Charles Shanley; Eric Irwin; Terry Pertile; Robert Kieval; Robert Cody
Journal: J Vasc Surg Date: 2006-12 Impact factor: 4.268

Implantable device therapy for the treatment of resistant hypertension.

1. Baroceptor function in chronic renal hypertension.

2. Influence of prolonged baroreflex activation on arterial pressure in angiotensin hypertension.

3. An implantable carotid sinus stimulator for drug-resistant hypertension: surgical technique and short-term outcome from the multicenter phase II Rheos feasibility trial.

4. Diminished baroreflex sensitivity in high blood pressure.

5. Effects of electrical stimulation of the carotid sinus nerve in reversal of experimentally induced hypertension.

6. Prevalence of drug resistant hypertension.

7. Baroreflexes prevent neurally induced sodium retention in angiotensin hypertension.

8. Acute sympathoexcitatory action of angiotensin II in conscious baroreceptor-denervated rats.

9. Prolonged activation of the baroreflex produces sustained hypotension.

10. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000.

Review 1. Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases.

2. Effects of low-level carotid baroreflex stimulation on atrial electrophysiology.