Literature DB >> 20556463

Stationary solutions for a modified Peyrard-Bishop DNA model with up to third-neighbor interactions.

Z Rapti1.   

Abstract

We investigate a DNA model that takes into account stacking interactions with neighbors up to three bases away. The model is a generalization of the well-known Peyrard-Bishop (PB) model and is motivated by studies that suggest that nearest-neighbor models for base-pair interaction in a DNA chain might not be enough to capture the mechanism and dynamics of DNA base-pair opening. We study stationary solutions of the modified model and investigate their stability. A comparison with the PB model reveals that under a wide range of parameter values the main characteristics of the original model --such as the hyperbolicity of the equilibrium at the origin-- are preserved, but new types of stationary solutions emerge.

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Year:  2010        PMID: 20556463     DOI: 10.1140/epje/i2010-10618-y

Source DB:  PubMed          Journal:  Eur Phys J E Soft Matter        ISSN: 1292-8941            Impact factor:   1.890


  15 in total

Review 1.  AdoMet-dependent methylation, DNA methyltransferases and base flipping.

Authors:  X Cheng; R J Roberts
Journal:  Nucleic Acids Res       Date:  2001-09-15       Impact factor: 16.971

2.  Base flipping in DNA: pathways and energetics studied with molecular dynamic simulations.

Authors:  Péter Várnai; Richard Lavery
Journal:  J Am Chem Soc       Date:  2002-06-26       Impact factor: 15.419

3.  Thermal denaturation of a helicoidal DNA model.

Authors:  Maria Barbi; Stefano Lepri; Michel Peyrard; Nikos Theodorakopoulos
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2003-12-23

Review 4.  Ten years of tension: single-molecule DNA mechanics.

Authors:  Carlos Bustamante; Zev Bryant; Steven B Smith
Journal:  Nature       Date:  2003-01-23       Impact factor: 49.962

5.  Statistical mechanics of a nonlinear model for DNA denaturation.

Authors: 
Journal:  Phys Rev Lett       Date:  1989-06-05       Impact factor: 9.161

6.  Nonlinear structures and thermodynamic instabilities in a one-dimensional lattice system.

Authors:  Nikos Theodorakopoulos; Michel Peyrard; Robert S Mackay
Journal:  Phys Rev Lett       Date:  2004-12-13       Impact factor: 9.161

7.  Sequence-dependent base pair opening in DNA double helix.

Authors:  Andrew Krueger; Ekaterina Protozanova; Maxim D Frank-Kamenetskii
Journal:  Biophys J       Date:  2006-02-24       Impact factor: 4.033

8.  On the discrete Peyrard-Bishop model of DNA: stationary solutions and stability.

Authors:  Sara Cuenda; Angel Sánchez
Journal:  Chaos       Date:  2006-06       Impact factor: 3.642

9.  Entropy-driven DNA denaturation.

Authors: 
Journal:  Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics       Date:  1993-01

10.  A nuclear magnetic resonance investigation of the energetics of basepair opening pathways in DNA.

Authors:  Daniel Coman; Irina M Russu
Journal:  Biophys J       Date:  2005-08-26       Impact factor: 4.033

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