Literature DB >> 20555169

Potential solutions to several vestibular challenges facing clinicians.

Daniel M Merfeld1, Adrian Priesol, Daniel Lee, Richard F Lewis.   

Abstract

Among other problems, patients with vestibular problems suffer imbalance, spatial disorientation, and blurred vision. These problems lead to varying degrees of disability and can be debilitating. Unfortunately, a large number of patients with vestibular complaints cannot be diagnosed with the clinical tests available today. Nor do we have treatments for all patients that we can diagnose. These clinical problems provide challenges to and opportunities for the field of vestibular research. In this paper, we discuss some new diagnostic and treatment options that could become available for tomorrow's patients. As a new diagnostic, we have begun measuring patient's perceptual direction-detection thresholds. Preliminary results appear encouraging; patients diagnosed with bilateral loss have yaw rotation thresholds almost ten times greater than normals, while patients diagnosed with migraine associated vertigo have roll tilt thresholds well below normal at 0.1 Hz. As a new treatment, we have performed animal studies looking at responses evoked by electrical stimulation provided by a vestibular prosthesis. Results measuring the VOR demonstrate promise and preliminary studies of balance and perception are also encouraging. While electrical stimulation is a standard means of stimulation, optical stimulation is also being investigated as a way to improve prosthetic stimulation specificity.

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Year:  2010        PMID: 20555169      PMCID: PMC2888506          DOI: 10.3233/VES-2010-0347

Source DB:  PubMed          Journal:  J Vestib Res        ISSN: 0957-4271            Impact factor:   2.435


  43 in total

1.  Prototype neural semicircular canal prosthesis using patterned electrical stimulation.

Authors:  W Gong; D M Merfeld
Journal:  Ann Biomed Eng       Date:  2000-05       Impact factor: 3.934

Review 2.  Balance prostheses for postural control.

Authors:  Conrad Wall; Marc S Weinberg
Journal:  IEEE Eng Med Biol Mag       Date:  2003 Mar-Apr

3.  Optical stimulation of the facial nerve: a new monitoring technique?

Authors:  Ingo Ulrik Teudt; Adam E Nevel; Agnella D Izzo; Joseph T Walsh; Claus-Peter Richter
Journal:  Laryngoscope       Date:  2007-09       Impact factor: 3.325

4.  Vestibular thresholds for yaw rotation about an earth-vertical axis as a function of frequency.

Authors:  Luzia Grabherr; Keyvan Nicoucar; Fred W Mast; Daniel M Merfeld
Journal:  Exp Brain Res       Date:  2008-03-19       Impact factor: 1.972

5.  The interrelations of migraine, vertigo, and migrainous vertigo.

Authors:  H Neuhauser; M Leopold; M von Brevern; G Arnold; T Lempert
Journal:  Neurology       Date:  2001-02-27       Impact factor: 9.910

6.  Roll tilt psychophysics in rhesus monkeys during vestibular and visual stimulation.

Authors:  Richard F Lewis; Csilla Haburcakova; Daniel M Merfeld
Journal:  J Neurophysiol       Date:  2008-04-16       Impact factor: 2.714

7.  Vibrotactile tilt feedback improves dynamic gait index: a fall risk indicator in older adults.

Authors:  Conrad Wall; Diane M Wrisley; Kennyn D Statler
Journal:  Gait Posture       Date:  2009-04-02       Impact factor: 2.840

8.  System design and performance of a unilateral horizontal semicircular canal prosthesis.

Authors:  Wangsong Gong; Daniel M Merfeld
Journal:  IEEE Trans Biomed Eng       Date:  2002-02       Impact factor: 4.538

9.  Prevalence of vertigo, dizziness, and migrainous vertigo in patients with migraine.

Authors:  Vlasta Vuković; Davor Plavec; Ivana Galinović; Arijana Lovrencić-Huzjan; Mislav Budisić; Vida Demarin
Journal:  Headache       Date:  2007 Nov-Dec       Impact factor: 5.887

10.  Vestibular perception in patients with acquired ophthalmoplegia.

Authors:  E A Grunfeld; J A Shallo-Hoffmann; L Cassidy; T Okada; M Faldon; J F Acheson; A M Bronstein
Journal:  Neurology       Date:  2003-06-24       Impact factor: 9.910

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  13 in total

1.  Clinical testing of otolith function: perceptual thresholds and myogenic potentials.

Authors:  Yuri Agrawal; Tatiana Bremova; Olympia Kremmyda; Michael Strupp; Paul R MacNeilage
Journal:  J Assoc Res Otolaryngol       Date:  2013-12

2.  Modeling direction discrimination thresholds for yaw rotations around an earth-vertical axis for arbitrary motion profiles.

Authors:  Florian Soyka; Paolo Robuffo Giordano; Michael Barnett-Cowan; Heinrich H Bülthoff
Journal:  Exp Brain Res       Date:  2012-05-24       Impact factor: 1.972

3.  A quantitative confidence signal detection model: 1. Fitting psychometric functions.

Authors:  Yongwoo Yi; Daniel M Merfeld
Journal:  J Neurophysiol       Date:  2016-01-13       Impact factor: 2.714

4.  Predicting direction detection thresholds for arbitrary translational acceleration profiles in the horizontal plane.

Authors:  Florian Soyka; Paolo Robuffo Giordano; Karl Beykirch; Heinrich H Bülthoff
Journal:  Exp Brain Res       Date:  2011-01-14       Impact factor: 1.972

5.  Human sensitivity to vertical self-motion.

Authors:  Alessandro Nesti; Michael Barnett-Cowan; Paul R Macneilage; Heinrich H Bülthoff
Journal:  Exp Brain Res       Date:  2013-10-25       Impact factor: 1.972

6.  Vestibular rehabilitation outcomes in patients with and without vestibular migraine.

Authors:  Jessica Vitkovic; Arimbi Winoto; Gary Rance; Richard Dowell; Mark Paine
Journal:  J Neurol       Date:  2013-09-24       Impact factor: 4.849

7.  Temporal processing of self-motion: modeling reaction times for rotations and translations.

Authors:  Florian Soyka; Heinrich H Bülthoff; Michael Barnett-Cowan
Journal:  Exp Brain Res       Date:  2013-05-12       Impact factor: 1.972

8.  Perspectives in vestibular diagnostics and therapy.

Authors:  Arneborg Ernst
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2012-04-26

9.  Self-motion sensitivity to visual yaw rotations in humans.

Authors:  Alessandro Nesti; Karl A Beykirch; Paolo Pretto; Heinrich H Bülthoff
Journal:  Exp Brain Res       Date:  2014-12-16       Impact factor: 1.972

10.  Comparison of linear motion perception thresholds in vestibular migraine and Menière's disease.

Authors:  Tatiana Bremova; Arla Caushaj; Matthias Ertl; Ralf Strobl; Nicolina Böttcher; Michael Strupp; Paul R MacNeilage
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-01-04       Impact factor: 2.503

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