| Literature DB >> 20554207 |
D Warther1, S Gug, A Specht, F Bolze, J-F Nicoud, A Mourot, M Goeldner.
Abstract
An uncaging process refers to a fast and efficient release of a biomolecule after photochemical excitation from a photoactivatable precursor. Two-photon excitation produces excited states identical to standard UV excitation while overcoming major limitations when dealing with biological materials, like spatial resolution, tissue penetration and toxicity and has therefore been applied to the uncaging of different biological effectors. A literature survey of two-photon uncaging of biomolecules is described in this article, including applications in cellular- and neurobiology.Entities:
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Year: 2010 PMID： 20554207 DOI： 10.1016/j.bmc.2010.04.084
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641