| Literature DB >> 20553039 |
Thorbjørn Terndrup Nielsen1, Véronique Wintgens, Catherine Amiel, Reinhard Wimmer, Kim Lambertsen Larsen.
Abstract
Three series of novel water-soluble beta-cyclodextrin-dextran polymers have been prepared by "click" chemistry. The polymers were synthesized from alkyne-modified dextrans (AMDs) onto which mono-6-O-deoxy-monoazido-betaCD (N3betaCD) was grafted by a copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The polymers have been characterized by NMR spectroscopy and size exclusion chromatography (SEC). The binding properties have been characterized by isothermal titration calorimetry (ITC) and show excellent accessibility of the betaCDs.Entities:
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Year: 2010 PMID: 20553039 DOI: 10.1021/bm9013233
Source DB: PubMed Journal: Biomacromolecules ISSN: 1525-7797 Impact factor: 6.988