| Literature DB >> 20550214 |
Yan Li1, Subin Niu, Bingda Sun, Shuchun Liu, Xingzhong Liu, Yongsheng Che.
Abstract
Cytosporolides A-C (1-3), three caryophyllene-derived meroterpenoids with a unique peroxylactone skeleton, were isolated from cultures of the fungus Cytospora sp. Their structures were elucidated by NMR spectroscopy, and the absolute configuration of the 5,6-diol moiety in 1 was assigned using Snatzke's method. Compounds 1-3 showed significant antimicrobial activity against the Gram-positive bacteria Staphylococcus aureus and Streptococcus pneumoniae.Entities:
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Year: 2010 PMID： 20550214 DOI： 10.1021/ol101062f
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005