| Literature DB >> 20548824 |
Michele Rossi1, Michael Lewis, Nevil Hutchinson.
Abstract
Patients with idiopathic thrombocytopenic purpura have safely undergone cardiac surgical procedures; however, platelets were transfused in 20 of 24 reported instances, and no point-of-care testing of coagulation status was performed. Herein, we report the case of a patient with idiopathic thrombocytopenic purpura who required urgent coronary artery bypass grafting and intra-aortic balloon pump support. Rotational thromboelastometry was used as a point-of-care test of the patient's coagulation status. No preoperative prophylactic transfusion of allogeneic platelets was necessary, and in fact the patient required no allogeneic blood products during his hospitalization. We believe that point-of-care coagulation tests such as thromboelastometry warrant further evaluation regarding their usefulness in the clinical decision of whether to transfuse platelets and other blood products.Entities:
Keywords: Blood coagulation disorders/diagnosis; blood coagulation tests; cardiopulmonary bypass; coronary disease/complications/surgery; hemostasis; platelet function tests/instrumentation/methods; preoperative care/methods; purpura, thrombocytopenic, idiopathic/complications/surgery; sensitivity and specificity; thrombelastography/instrumentation/methods
Mesh:
Year: 2010 PMID: 20548824 PMCID: PMC2879213
Source DB: PubMed Journal: Tex Heart Inst J ISSN: 0730-2347