Literature DB >> 20543574

SWItching on the transcriptional circuitry in melanoma.

Srinivas Vinod Saladi1, Himangi Marathe, Ivana L de la Serna.   

Abstract

Melanoma is an aggressive malignancy that is resistant to current therapy, and the most lethal of all human skin cancers. It is characterized by several genetic alterations that lead to changes in gene expression and tumorigenesis by triggering alterations in the normal transcriptional circuitry. Transformation and tumor progression are thought to be promoted by a complex interplay between the accumulation of genetic alterations and epigenetic changes. In this review, we discuss recent studies that have implicated SWI/SNF chromatin remodeling enzymes as epigenetic regulators of a transcriptional circuit that operates within the context the genetic alterations that frequently occur in melanoma.

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Year:  2010        PMID： 20543574      PMCID： PMC3230549          DOI： 10.4161/epi.5.6.12315

Source DB:  PubMed          Journal:  Epigenetics        ISSN： 1559-2294            Impact factor:   4.528


  87 in total

1.  The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

Authors:  M D Galibert; S Carreira; C R Goding
Journal:  EMBO J       Date:  2001-09-03       Impact factor: 11.598

2.  BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation.

Authors:  Jeonghyeon Park; Marcelo A Wood; Michael D Cole
Journal:  Mol Cell Biol       Date:  2002-03       Impact factor: 4.272

3.  Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes.

Authors:  Borja Belandia; Rob L Orford; Helen C Hurst; Malcolm G Parker
Journal:  EMBO J       Date:  2002-08-01       Impact factor: 11.598

4.  Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

Authors:  Shilpa Kadam; Beverly M Emerson
Journal:  Mol Cell       Date:  2003-02       Impact factor: 17.970

5.  Mammalian SWI/SNF chromatin remodeling complexes are required to prevent apoptosis after DNA damage.

Authors:  Ji-Hye Park; Eun-Jung Park; Shin-Kyoung Hur; Sungsu Kim; Jongbum Kwon
Journal:  DNA Repair (Amst)       Date:  2008-10-07

6.  Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

Authors:  Bryan L Betz; Matthew W Strobeck; David N Reisman; Erik S Knudsen; Bernard E Weissman
Journal:  Oncogene       Date:  2002-08-08       Impact factor: 9.867

7.  Increased expression but not genetic alteration of BRG1, a component of the SWI/SNF complex, is associated with the advanced stage of human gastric carcinomas.

Authors:  K Sentani; N Oue; H Kondo; K Kuraoka; J Motoshita; R Ito; H Yokozaki; W Yasui
Journal:  Pathobiology       Date:  2001       Impact factor: 4.342

8.  High frequency of BRAF mutations in nevi.

Authors:  Pamela M Pollock; Ursula L Harper; Katherine S Hansen; Laura M Yudt; Mitchell Stark; Christiane M Robbins; Tracy Y Moses; Galen Hostetter; Urs Wagner; John Kakareka; Ghadi Salem; Tom Pohida; Peter Heenan; Paul Duray; Olli Kallioniemi; Nicholas K Hayward; Jeffrey M Trent; Paul S Meltzer
Journal:  Nat Genet       Date:  2002-11-25       Impact factor: 38.330

9.  Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.

Authors:  Gaël G McGill; Martin Horstmann; Hans R Widlund; Jinyan Du; Gabriela Motyckova; Emi K Nishimura; Yi-Ling Lin; Sridhar Ramaswamy; William Avery; Han-Fei Ding; Siobhán A Jordan; Ian J Jackson; Stanley J Korsmeyer; Todd R Golub; David E Fisher
Journal:  Cell       Date:  2002-06-14       Impact factor: 41.582

10.  Mutations of the BRAF gene in human cancer.

Authors:  Helen Davies; Graham R Bignell; Charles Cox; Philip Stephens; Sarah Edkins; Sheila Clegg; Jon Teague; Hayley Woffendin; Mathew J Garnett; William Bottomley; Neil Davis; Ed Dicks; Rebecca Ewing; Yvonne Floyd; Kristian Gray; Sarah Hall; Rachel Hawes; Jaime Hughes; Vivian Kosmidou; Andrew Menzies; Catherine Mould; Adrian Parker; Claire Stevens; Stephen Watt; Steven Hooper; Rebecca Wilson; Hiran Jayatilake; Barry A Gusterson; Colin Cooper; Janet Shipley; Darren Hargrave; Katherine Pritchard-Jones; Norman Maitland; Georgia Chenevix-Trench; Gregory J Riggins; Darell D Bigner; Giuseppe Palmieri; Antonio Cossu; Adrienne Flanagan; Andrew Nicholson; Judy W C Ho; Suet Y Leung; Siu T Yuen; Barbara L Weber; Hilliard F Seigler; Timothy L Darrow; Hugh Paterson; Richard Marais; Christopher J Marshall; Richard Wooster; Michael R Stratton; P Andrew Futreal
Journal:  Nature       Date:  2002-06-09       Impact factor: 49.962
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  4 in total

Review 1.  Epigenetic regulation in human melanoma: past and future.

Authors:  Debina Sarkar; Euphemia Y Leung; Bruce C Baguley; Graeme J Finlay; Marjan E Askarian-Amiri
Journal:  Epigenetics       Date:  2015       Impact factor: 4.528

2.  MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.

Authors:  Lubica Ondrušová; Jiri Vachtenheim; Jiri Réda; Petra Záková; Kamila Benková
Journal:  PLoS One       Date:  2013-01-17       Impact factor: 3.240

3.  BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation.

Authors:  Himangi G Marathe; Dawn E Watkins-Chow; Matthias Weider; Alana Hoffmann; Gaurav Mehta; Archit Trivedi; Shweta Aras; Tupa Basuroy; Aanchal Mehrotra; Dorothy C Bennett; Michael Wegner; William J Pavan; Ivana L de la Serna
Journal:  Nucleic Acids Res       Date:  2017-06-20       Impact factor: 16.971

Review 4.  Extracellular Vesicles and Epigenetic Modifications Are Hallmarks of Melanoma Progression.

Authors:  Francesco Mannavola; Stella D'Oronzo; Mauro Cives; Luigia Stefania Stucci; Girolamo Ranieri; Franco Silvestris; Marco Tucci
Journal:  Int J Mol Sci       Date:  2019-12-20       Impact factor: 5.923
  4 in total

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