Literature DB >> 20538015

HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors.

Silke Wissing1, Nicole L K Galloway, Warner C Greene.   

Abstract

The Vif protein of HIV is essential for the effective propagation of this pathogenic retrovirus in vivo. Vif acts by preventing virion encapsidation of two potent antiviral factors, the APOBEC3G and APOBEC3F cytidine deaminases. Decreased encapsidation in part involves Vif-mediated recruitment of a ubiquitin E3 ligase complex that promotes polyubiquitylation and proteasome-mediated degradation of APOBEC3G/F. The resultant decline in intracellular levels of these enzymes leads to decreased encapsidation of APOBECG/F into budding virions. This review discusses recent advances in our understanding of the dynamic interplay of Vif with the antiviral APOBEC3 enzymes.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20538015      PMCID： PMC2967609          DOI： 10.1016/j.mam.2010.06.001

Source DB:  PubMed          Journal:  Mol Aspects Med        ISSN： 0098-2997


  196 in total

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Authors:  Adam Jarmuz; Ann Chester; Jayne Bayliss; Jane Gisbourne; Ian Dunham; James Scott; Naveenan Navaratnam
Journal:  Genomics       Date:  2002-03       Impact factor: 5.736

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Authors:  Ying Dang; Roderick W Davis; Ian A York; Yong-Hui Zheng
Journal:  J Virol       Date:  2010-03-24       Impact factor: 5.103

3.  Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation.

Authors:  Andrew Mehle; Joao Goncalves; Mariana Santa-Marta; Mark McPike; Dana Gabuzda
Journal:  Genes Dev       Date:  2004-12-01       Impact factor: 11.361

4.  APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

Authors:  Linda Chelico; Phuong Pham; Peter Calabrese; Myron F Goodman
Journal:  Nat Struct Mol Biol       Date:  2006-04-23       Impact factor: 15.369

5.  Mutational alteration of human immunodeficiency virus type 1 Vif allows for functional interaction with nonhuman primate APOBEC3G.

Authors:  Bärbel Schröfelbauer; Tilo Senger; Gerard Manning; Nathaniel R Landau
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

6.  Human immunodeficiency virus type 1 Vif protein is packaged into the nucleoprotein complex through an interaction with viral genomic RNA.

Authors:  M A Khan; C Aberham; S Kao; H Akari; R Gorelick; S Bour; K Strebel
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

7.  Enzymatically active APOBEC3G is required for efficient inhibition of human immunodeficiency virus type 1.

Authors:  Eri Miyagi; Sandrine Opi; Hiroaki Takeuchi; Mohammad Khan; Ritu Goila-Gaur; Sandra Kao; Klaus Strebel
Journal:  J Virol       Date:  2007-10-10       Impact factor: 5.103

8.  Functional domain organization of human APOBEC3G.

Authors:  Barry D Gooch; Bryan R Cullen
Journal:  Virology       Date:  2008-07-18       Impact factor: 3.616

9.  Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant.

Authors:  Sandrine Opi; Sandra Kao; Ritu Goila-Gaur; Mohammad A Khan; Eri Miyagi; Hiroaki Takeuchi; Klaus Strebel
Journal:  J Virol       Date:  2007-05-23       Impact factor: 5.103

10.  RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1.

Authors:  Hendrik Huthoff; Flavia Autore; Sarah Gallois-Montbrun; Franca Fraternali; Michael H Malim
Journal:  PLoS Pathog       Date:  2009-03-06       Impact factor: 6.823
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  36 in total

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Journal:  Cell Mol Life Sci       Date:  2011-10-28       Impact factor: 9.261

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Authors:  Sean R Marcsisin; Purushottam S Narute; Lori A Emert-Sedlak; Marek Kloczewiak; Thomas E Smithgall; John R Engen
Journal:  J Mol Biol       Date:  2011-07-29       Impact factor: 5.469

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Authors:  Tali H Reingewertz; Elena Britan-Rosich; Shahar Rotem-Bamberger; Mathias Viard; Amy Jacobs; Abigail Miller; Ji Youn Lee; Jeeseong Hwang; Robert Blumenthal; Moshe Kotler; Assaf Friedler
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Authors:  Claudio Fenizia; Martina Fiocchi; Kathryn Jones; Robyn Washington Parks; Michele Ceribelli; Sebastien A Chevalier; Dustin Edwards; Francis Ruscetti; Cynthia A Pise-Masison; Genoveffa Franchini
Journal:  J Virol       Date:  2013-10-23       Impact factor: 5.103

7.  Alteration of select gene expression patterns in individuals infected with HIV-1.

Authors:  Erik Serrao; Chia-Hao Wang; Toinette Frederick; Chi-Lin Lee; Patricia Anthony; David Arribas-Layton; Kerry Baker; Joshua Millstein; Andrea Kovacs; Nouri Neamati
Journal:  J Med Virol       Date:  2014-01-30       Impact factor: 2.327

8.  An intronic G run within HIV-1 intron 2 is critical for splicing regulation of vif mRNA.

Authors:  Marek Widera; Steffen Erkelenz; Frank Hillebrand; Aikaterini Krikoni; Darius Widera; Wolfgang Kaisers; René Deenen; Michael Gombert; Rafael Dellen; Tanya Pfeiffer; Barbara Kaltschmidt; Carsten Münk; Valerie Bosch; Karl Köhrer; Heiner Schaal
Journal:  J Virol       Date:  2012-12-19       Impact factor: 5.103

9.  The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution.

Authors:  Anurag Rathore; Michael A Carpenter; Özlem Demir; Terumasa Ikeda; Ming Li; Nadine M Shaban; Emily K Law; Dmitry Anokhin; William L Brown; Rommie E Amaro; Reuben S Harris
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10.  Efficient transduction of human hematopoietic repopulating cells with a chimeric HIV1-based vector including SIV capsid.

Authors:  Naoya Uchida; Matthew M Hsieh; Kareem N Washington; John F Tisdale
Journal:  Exp Hematol       Date:  2013-05-09       Impact factor: 3.084
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