| Literature DB >> 20537720 |
Qian Zhao1, Ronglin Che, Zhao Zhang, Peng Wang, Jun Li, You Li, Ke Huang, Wei Tang, Guoyin Feng, Klaus Lindpaintner, Lin He, Yongyong Shi.
Abstract
In the present work we genotyped three single-nucleotide polymorphisms (SNPs) (rs7301328, rs1805247, and rs1805502) of the GRIN2B gene in a set of 480 unrelated bipolar disorder patients and 480 unrelated genetically matched normal controls in Chinese Han population by either allelic-specific multiplex ligation-detection reaction (AMLR) technology or direct sequencing. Rs1805247 and the haplotype consisting of rs1805502 and rs1805247 were significantly associated, suggesting GRIN2B as having a role in the etiology of bipolar disorder.Entities:
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Year: 2010 PMID： 20537720 DOI： 10.1016/j.psychres.2009.11.026
Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222