Literature DB >> 20534797

GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene.

Diana E Ciardo1, Sibylle Burger, Michael Payer, Christian Lee, Nadine McCallum.   

Abstract

A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCCmec upon subculturing in vitro, indicating that unstable MRSA is best detected by gene amplification-based methods.

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Year:  2010        PMID： 20534797      PMCID： PMC2916610          DOI： 10.1128/JCM.02113-09

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  19 in total

1.  Improved methods for detection of methicillin-resistant Staphylococcus aureus.

Authors:  S Rohrer; M Tschierske; R Zbinden; B Berger-Bächi
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2001-04       Impact factor: 3.267

2.  Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus.

Authors:  Duarte C Oliveira; Hermínia de Lencastre
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191

3.  Are all community methicillin-resistant Staphylococcus aureus related? A comparison of their mec regions.

Authors:  Tien Tze Lim; Fuen Nie Chong; Frances G O'Brien; Warren B Grubb
Journal:  Pathology       Date:  2003-08       Impact factor: 5.306

4.  Survey of the methicillin resistance-associated genes mecA, mecR1-mecI, and femA-femB in clinical isolates of methicillin-resistant Staphylococcus aureus.

Authors:  R L Hürlimann-Dalel; C Ryffel; F H Kayser; B Berger-Bächi
Journal:  Antimicrob Agents Chemother       Date:  1992-12       Impact factor: 5.191

5.  Loss of the mecA gene during storage of methicillin-resistant Staphylococcus aureus strains.

Authors:  Arjanne van Griethuysen; Inge van Loo; Alex van Belkum; Christina Vandenbroucke-Grauls; Wim Wannet; Peter van Keulen; Jan Kluytmans
Journal:  J Clin Microbiol       Date:  2005-03       Impact factor: 5.948

Review 6.  Meticillin resistant Staphylococcus aureus in the hospital.

Authors:  Jan Kluytmans; Marc Struelens
Journal:  BMJ       Date:  2009-02-12

7.  Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus.

Authors:  T Ito; Y Katayama; K Asada; N Mori; K Tsutsumimoto; C Tiensasitorn; K Hiramatsu
Journal:  Antimicrob Agents Chemother       Date:  2001-05       Impact factor: 5.191

8.  Genetic background affects stability of mecA in Staphylococcus aureus.

Authors:  Yuki Katayama; D Ashley Robinson; Mark C Enright; Henry F Chambers
Journal:  J Clin Microbiol       Date:  2005-05       Impact factor: 5.948

9.  Novel staphylococcal cassette chromosome mec type, tentatively designated type VIII, harboring class A mec and type 4 ccr gene complexes in a Canadian epidemic strain of methicillin-resistant Staphylococcus aureus.

Authors:  Kunyan Zhang; Jo-Ann McClure; Sameer Elsayed; John M Conly
Journal:  Antimicrob Agents Chemother       Date:  2008-12-08       Impact factor: 5.191

10.  Multiplex real-time PCR for rapid Staphylococcal cassette chromosome mec typing.

Authors:  Liang Chen; José R Mediavilla; Duarte C Oliveira; Barbara M Willey; Herminia de Lencastre; Barry N Kreiswirth
Journal:  J Clin Microbiol       Date:  2009-09-02       Impact factor: 5.948
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  4 in total

1.  Characterization of the staphylococcal cassette chromosome mec insertion site in 108 isolates lacking the mecA gene and identified as methicillin-resistant Staphylococcus aureus by the Xpert MRSA assay.

Authors:  M Stojanov; D S Blanc
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-06-07       Impact factor: 3.267

2.  Screening agars for MRSA: evaluation of a stepwise diagnostic approach with two different selective agars for the screening for methicillin-resistant Staphylococcus aureus (MRSA).

Authors:  Volker Micheel; Benedikt Hogan; Thomas Köller; Philipp Warnke; Sabine Crusius; Rebecca Hinz; Ralf Matthias Hagen; Norbert Georg Schwarz; Hagen Frickmann
Journal:  Mil Med Res       Date:  2015-07-21

Review 3.  A Comprehensive Overview of Antibiotic Selection and the Factors Affecting It.

Authors:  Karan Patel; Sean Bunachita; Ank A Agarwal; Akshay Bhamidipati; Urvish K Patel
Journal:  Cureus       Date:  2021-03-16

4.  Detection of Methicillin-Resistant Staphylococcus aureus Infections Using Molecular Methods.

Authors:  Fred C Tenover; Isabella A Tickler
Journal:  Antibiotics (Basel)       Date:  2022-02-12
  4 in total

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