| Literature DB >> 2053137 |
F M Jeffrey1, A Rajagopal, C R Malloy, A D Sherry.
Abstract
13C-NMR is a particularly attractive tool for metabolic studies because of its inherent simplicity: all labeled products at sufficient concentration may be identified and analysed in a single spectrum. However, the real power behind the approach presented here is the ability to measure groups of individual 13C-isotopomers (isotope isomers). The information that this provides is superior to conventional tracer techniques, allowing a very detailed description of metabolic events. Several examples are given of the value of this convenient and straightforward analysis for some problems of current interest in intermediary metabolism.Entities:
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Year: 1991 PMID： 2053137 DOI： 10.1016/0968-0004(91)90004-f
Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807