PURPOSE: To develop a method for visualizing surgical textile implant (STI) with superparamagnetic iron oxides (SPIO), using magnetic resonance imaging (MRI). Therefore, positive-contrast inversion-recovery with on-resonant water suppression (IRON) was applied and its properties were evaluated in vitro. MATERIALS AND METHODS: STI with different concentrations of SPIO integrated into the base material were produced. Imaging was performed on a clinical 1.5 Tesla scanner, using conventional balanced gradient echo sequences (SSFP), T2*-weighted sequences, and IRON-imaging. In vitro experiments were conducted in an agarose phantom. On MR-images, contrast-to-noise-ratios, and the dimensions of the implant were assessed. RESULTS: Conventional MRI exhibited SPIO-loaded STI as signal voids. Using IRON, the mesh was clearly exhibited hyperintensely with suppression of on-resonant background signals with a distinct differentiation to other sources of off-resonances. Concentrations of approximately 9 mg/g led to best positive contrast and highest contrast-to-noise-ratios using IRON. Depending on B0-orientation, phase encoding direction and the STI's SPIO-load, the IRON-signal showed a characteristic pattern and an overestimation of STI size up to 4.6 mm. CONCLUSION: The integration of SPIOs into the base material combined with IRON is a feasible approach to visualize STI with MRI. This method could help to identify mesh-related problems in time and to reduce the need for surgical revision.
PURPOSE: To develop a method for visualizing surgical textile implant (STI) with superparamagnetic iron oxides (SPIO), using magnetic resonance imaging (MRI). Therefore, positive-contrast inversion-recovery with on-resonant water suppression (IRON) was applied and its properties were evaluated in vitro. MATERIALS AND METHODS: STI with different concentrations of SPIO integrated into the base material were produced. Imaging was performed on a clinical 1.5 Tesla scanner, using conventional balanced gradient echo sequences (SSFP), T2*-weighted sequences, and IRON-imaging. In vitro experiments were conducted in an agarose phantom. On MR-images, contrast-to-noise-ratios, and the dimensions of the implant were assessed. RESULTS: Conventional MRI exhibited SPIO-loaded STI as signal voids. Using IRON, the mesh was clearly exhibited hyperintensely with suppression of on-resonant background signals with a distinct differentiation to other sources of off-resonances. Concentrations of approximately 9 mg/g led to best positive contrast and highest contrast-to-noise-ratios using IRON. Depending on B0-orientation, phase encoding direction and the STI's SPIO-load, the IRON-signal showed a characteristic pattern and an overestimation of STI size up to 4.6 mm. CONCLUSION: The integration of SPIOs into the base material combined with IRON is a feasible approach to visualize STI with MRI. This method could help to identify mesh-related problems in time and to reduce the need for surgical revision.
Authors: Nikhil Sindhwani; Andrew Feola; Frederik De Keyzer; Filip Claus; Geertje Callewaert; Iva Urbankova; Sebastien Ourselin; Jan D'hooge; Jan Deprest Journal: Int Urogynecol J Date: 2015-03-24 Impact factor: 2.894
Authors: J Otto; D Busch; C Klink; A Ciritsis; A Woitok; C Kuhl; U Klinge; U P Neumann; N A Kraemer; J Conze Journal: Hernia Date: 2014-06-10 Impact factor: 4.739
Authors: Masayuki Endo; Andrew Feola; Nikhil Sindhwani; Stefano Manodoro; Jarek Vlacil; Alexander Carl Engels; Filip Claus; Jan A Deprest Journal: Int Urogynecol J Date: 2014-01-22 Impact factor: 2.894
Authors: Marites P Melancon; Andrew Elliott; Xiaojun Ji; Anil Shetty; Zhi Yang; Mei Tian; Brian Taylor; R Jason Stafford; Chun Li Journal: Invest Radiol Date: 2011-02 Impact factor: 6.016
Authors: Nicolas Kuehnert; Nils A Kraemer; Jens Otto; Hank C W Donker; Ioana Slabu; Martin Baumann; Christiane K Kuhl; Uwe Klinge Journal: Surg Endosc Date: 2011-12-17 Impact factor: 4.584