Literature DB >> 20530884

Differential substrate specificity of two inositol transporters of Bacillus subtilis.

Tetsuro Morinaga1, Takatsugu Matsuse, Hitoshi Ashida, Ken-ichi Yoshida.   

Abstract

Bacillus subtilis IolT is the major myo-inositol transporter for growth, while IolF is a minor one unable to support growth. We found that either IolT or IolF was sufficient for moderate growth using D-chiro-inositol. Conversely to IolT, IolF transported D-chiro-inositol more preferentially than myo-inositol. These results indicate that IolT and IolF are different in substrate specificity.

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Year:  2010        PMID： 20530884     DOI： 10.1271/bbb.100125

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  6 in total

1.  A second-generation Bacillus cell factory for rare inositol production.

Authors:  Kosei Tanaka; Shinji Takanaka; Ken-ichi Yoshida
Journal:  Bioengineered       Date:  2014 Sep-Oct       Impact factor: 3.269

2.  A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease.

Authors:  Masaru Yamaoka; Shin Osawa; Tetsuro Morinaga; Shinji Takenaka; Ken-ichi Yoshida
Journal:  Microb Cell Fact       Date:  2011-09-07       Impact factor: 5.328

3.  Bacillus subtilis IolQ (DegA) is a transcriptional repressor of iolX encoding NAD+-dependent scyllo-inositol dehydrogenase.

Authors:  Dong-Min Kang; Christophe Michon; Tetsuro Morinaga; Kosei Tanaka; Shinji Takenaka; Shu Ishikawa; Ken-Ichi Yoshida
Journal:  BMC Microbiol       Date:  2017-07-11       Impact factor: 3.605

4.  A bacterial cell factory converting glucose into scyllo-inositol, a therapeutic agent for Alzheimer's disease.

Authors:  Christophe Michon; Choong-Min Kang; Sophia Karpenko; Kosei Tanaka; Shu Ishikawa; Ken-Ichi Yoshida
Journal:  Commun Biol       Date:  2020-03-02

5.  An improved Bacillus subtilis cell factory for producing scyllo-inositol, a promising therapeutic agent for Alzheimer's disease.

Authors:  Kosei Tanaka; Shintaro Tajima; Shinji Takenaka; Ken-ichi Yoshida
Journal:  Microb Cell Fact       Date:  2013-12-11       Impact factor: 5.328

6.  A new-generation of Bacillus subtilis cell factory for further elevated scyllo-inositol production.

Authors:  Kosei Tanaka; Ayane Natsume; Shu Ishikawa; Shinji Takenaka; Ken-Ichi Yoshida
Journal:  Microb Cell Fact       Date:  2017-04-21       Impact factor: 5.328
  6 in total

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