Literature DB >> 20526432

An expedient reductive method for conversion of ketoximes to the corresponding carbonyl compounds.

Max M Majireck1, Jason A Witek, Steven M Weinreb.   

Abstract

A wide array of readily prepared pivalates of ketoximes can be converted to the corresponding ketones in good yields by treatment with iron powder in THF containing catalytic amounts of both trimethylsilyl chloride and glacial acetic acid at room temperature for 30 minutes, followed by a brief aqueous workup.

Entities:  

Year:  2010        PMID: 20526432      PMCID: PMC2880526          DOI: 10.1016/j.tetlet.2010.04.131

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN: 0040-4039            Impact factor:   2.415


  5 in total

1.  A Three-Step Procedure for Asymmetric Catalytic Reductive Amidation of Ketones.

Authors:  Mark J. Burk; Guy Casy; Nicholas B. Johnson
Journal:  J Org Chem       Date:  1998-09-04       Impact factor: 4.354

2.  First enantiospecific total synthesis of the antitubercular marine natural product pseudopteroxazole. Revision of assigned stereochemistry.

Authors:  James P Davidson; E J Corey
Journal:  J Am Chem Soc       Date:  2003-11-05       Impact factor: 15.419

3.  Construction of bridged and fused ring systems via intramolecular Michael reactions of vinylnitroso compounds.

Authors:  Ilia Korboukh; Praveen Kumar; Steven M Weinreb
Journal:  J Am Chem Soc       Date:  2007-08-03       Impact factor: 15.419

4.  Efficient methodology for alkylation of vinylnitroso compounds with carbon nucleophiles.

Authors:  Puhui Li; Max M Majireck; Jason A Witek; Steven M Weinreb
Journal:  Tetrahedron Lett       Date:  2010-04-14       Impact factor: 2.415

5.  Pd-catalyzed carboetherification of beta,gamma-unsaturated oximes: a novel approach to Delta2-isoxazolines.

Authors:  Dahong Jiang; Jinsong Peng; Yuanwei Chen
Journal:  Org Lett       Date:  2008-04-08       Impact factor: 6.005

  5 in total
  2 in total

1.  An enantiospecific synthesis of jiadifenolide.

Authors:  David A Siler; Jeffrey D Mighion; Erik J Sorensen
Journal:  Angew Chem Int Ed Engl       Date:  2014-04-23       Impact factor: 15.336

2.  SnCl2/TiCl3-mediated deoximation of oximes in an aqueous solvent.

Authors:  Mei-Huey Lin; Han-Jun Liu; Cheng-Yu Chang; Wei-Cheng Lin; Tsung-Hsun Chuang
Journal:  Molecules       Date:  2012-03-01       Impact factor: 4.411

  2 in total

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