Literature DB >> 20525187

The deployment of a tissue request tracking system for the CHTN: a case study in managing change in informatics for biobanking operations.

Mary E Edgerton1, William E Grizzle, M Kay Washington.   

Abstract

BACKGROUND: Managing change has not only been recognized as an important topic in medical informatics, but it has become increasingly important in translational informatics. The move to share data, together with the increasing complexity and volume of the data, has precipitated a transition from locally stored worksheet and flat files to relational data bases with object oriented interfaces for data storage and retrieval. While the transition from simple to complex data structures, mirroring the transition from simple to complex experimental technologies, seems natural, the human factor often fails to be adequately addressed leading to failures in managing change.
METHODS: We describe here a case study in change management applied to an application in translational informatics that touches upon changes in hardware, software, data models, procedures, and terminology standards. We use the classic paper by Riley and Lorenzi to dissect the problems that arose, the solutions that were implemented, and the lessons learned.
RESULTS: The entire project from requirements gathering through completion of migration of the system took three years. Double data entry into the old and new systems persisted for six months. Contributing factors hindering progress and solutions to facilitate managing the change were identified in seven of the areas identified by Riley and Lorenzi: communications, cultural changes in work practice, scope creep, leadership and organizational issues, and training.
CONCLUSIONS: Detailed documentation of the agreed upon requirements for the new system along with ongoing review of the sources of resistance to change as defined by Riley and Lorenzi were the most important steps taken that contributed to the success of the project. Cultural changes in tissue collection mandated by standards requirements introduced by the Cancer Bioinformatics Grid (CaBIG) and excessive reliance on the outgoing system during a lengthy period of dual data entry were the primary sources of resistance to change.

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Year:  2010        PMID: 20525187      PMCID: PMC2893081          DOI: 10.1186/1472-6947-10-32

Source DB:  PubMed          Journal:  BMC Med Inform Decis Mak        ISSN: 1472-6947            Impact factor:   2.796


  8 in total

Review 1.  The Nursing Terminology Summit Conferences: a case study of successful collaboration for change.

Authors:  Judy Ozbolt
Journal:  J Biomed Inform       Date:  2003 Aug-Oct       Impact factor: 6.317

2.  Infrastructure for a learning health care system: CaBIG.

Authors:  Kenneth H Buetow; John Niederhuber
Journal:  Health Aff (Millwood)       Date:  2009 May-Jun       Impact factor: 6.301

3.  Managing change: an overview.

Authors:  N M Lorenzi; R T Riley
Journal:  J Am Med Inform Assoc       Date:  2000 Mar-Apr       Impact factor: 4.497

4.  Individualizing cancer care with interoperable information systems.

Authors:  Kathleen A McCormick
Journal:  Stud Health Technol Inform       Date:  2009

5.  The Cooperative Human Tissue Network. An update.

Authors:  V A LiVolsi; K P Clausen; W Grizzle; W Newton; T G Pretlow; R Aamodt
Journal:  Cancer       Date:  1993-02-15       Impact factor: 6.860

6.  Special communication. The Cooperative Human Tissue Network.

Authors:  K P Clausen; W E Grizzle; V Livolsi; W A Newton; R Aamodt
Journal:  Cancer       Date:  1989-04-01       Impact factor: 6.860

7.  Key issues in reporting common cancer specimens: problems in pathologic staging of colon cancer.

Authors:  Carolyn C Compton
Journal:  Arch Pathol Lab Med       Date:  2006-03       Impact factor: 5.534

8.  A standards based ontological approach to information handling for use by organizations providing human tissue for research.

Authors:  Mary E Edgerton; Carl Morrison; Virginia A LiVolsi; Christopher A Moskaluk; Stephen J Qualman; M Kay Washington; William E Grizzle
Journal:  Cancer Inform       Date:  2008-04-10
  8 in total
  2 in total

1.  Issues in collecting, processing and storing human tissues and associated information to support biomedical research.

Authors:  William E Grizzle; Walter C Bell; Katherine C Sexton
Journal:  Cancer Biomark       Date:  2010       Impact factor: 4.388

2.  Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity.

Authors:  Joseph C Chen; Jacquelyn R Hoffman; Ripla Arora; Lila A Perrone; Christian J Gonzalez-Gomez; Kim Chi Vo; Diana J Laird; Juan C Irwin; Linda C Giudice
Journal:  Fertil Steril       Date:  2015-10-26       Impact factor: 7.329

  2 in total

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