Literature DB >> 20521800

ROMP-derived oligomeric phosphates for application in facile benzylation.

Toby R Long1, Pradip K Maity, Thiwanka B Samarakoon, Paul R Hanson.   

Abstract

The development of new ROMP-based oligomeric benzyl phosphates (OBP(n)) is reported for use as soluble, stable benzylating reagents. These oligomeric reagents are readily synthesized from commercially available materials and conveniently polymerized and purified in a one-pot process, affording bench-stable, pure white, free-flowing solids on multigram scale. Utilization in benzylation reactions with a variety of nucleophiles is reported.

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Year:  2010        PMID： 20521800      PMCID： PMC2925234          DOI： 10.1021/ol1006604

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  33 in total

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  10 in total

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  10 in total

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