Literature DB >> 20518279

Molecular analysis of two novel Neisseria gonorrhoeae virulent components: the macrophage infectivity potentiator and the outer membrane protein A.

Stefania Starnino1, Rosanna Leuzzi, Valeria Ghisetti, Maria Antonia De Francesco, Marco Cusini, Giampaolo Impara, Emma Galluppi, Mariagrazia Pizza, Paola Stefanelli.   

Abstract

Molecular analyses of mip and ompA genes were performed on 20 Neisseria gonorrhoeae isolates. The genes were present with a high degree of conservation in all strains. Sera from patients with urethritis or disseminated gonococcal infections were able to recognize the purified Neisseria gonorrhoeae macrophage infectivity potentiator (Ng-MIP) and Neisseria gonorrhoeae outer membrane protein A (Ng-OmpA).

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Year:  2010        PMID： 20518279

Source DB:  PubMed          Journal:  New Microbiol        ISSN： 1121-7138            Impact factor:   2.479


  6 in total

1.  Identification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response.

Authors:  Manish Mahawar; Maninjay K Atianand; Rachel J Dotson; Vanessa Mora; Seham M Rabadi; Dennis W Metzger; Jason F Huntley; Jonathan A Harton; Meenakshi Malik; Chandra Shekhar Bakshi
Journal:  J Biol Chem       Date:  2012-05-31       Impact factor: 5.157

2.  Characterization of Francisella tularensis Schu S4 defined mutants as live-attenuated vaccine candidates.

Authors:  Araceli E Santiago; Barbara J Mann; Aiping Qin; Aimee L Cunningham; Leah E Cole; Christen Grassel; Stefanie N Vogel; Myron M Levine; Eileen M Barry
Journal:  Pathog Dis       Date:  2015-05-17       Impact factor: 3.166

3.  Comparative proteomics analysis of Neisseria gonorrhoeae strains in response to extended-spectrum cephalosporins.

Authors:  Sunanta Nabu; Ratana Lawung; Patcharee Isarankura-Na-Ayudhya; Sittiruk Roytrakul; Supamas Dolprasit; Sineenart Sengyee; Chartchalerm Isarankura-Na-Ayudhya; Virapong Prachayasittikul
Journal:  EXCLI J       Date:  2017-11-08       Impact factor: 4.068

4.  Immunization with recombinant truncated Neisseria meningitidis-Macrophage Infectivity Potentiator (rT-Nm-MIP) protein induces murine antibodies that are cross-reactive and bactericidal for Neisseria gonorrhoeae.

Authors:  María Victoria Humbert; Myron Christodoulides
Journal:  Vaccine       Date:  2018-05-24       Impact factor: 3.641

5.  Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus.

Authors:  Maria Victoria Humbert; Alexandra Jackson; Christian M Orr; Ivo Tews; Myron Christodoulides
Journal:  Sci Rep       Date:  2019-07-11       Impact factor: 4.379

Review 6.  Update on the Neisseria Macrophage Infectivity Potentiator-Like PPIase Protein.

Authors:  Myron Christodoulides
Journal:  Front Cell Infect Microbiol       Date:  2022-03-22       Impact factor: 5.293
  6 in total

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