Literature DB >> 205151

Hand-to-hand transmission of rhinovirus colds.

J M Gwaltney, P B Moskalski, J O Hendley.   

Abstract

Rhinovirus was transmitted from experimentally infected volunteers (donors) to susceptible recipients and the efficiencies of spread by hand-to-hand contact and large- and small-particle aerosols compared. Transmission of infection was very efficient by the hand route: 11 of 15 hand-contact exposures initiated infection, compared with one of 12 large-particle (P less than 0.005) and none of 10 small-particle (P less than 0.005) exposures. Rhinovirus was present in nine of 18 (50%) nasal swab specimens, 28 of 43 (65%) hand rinses, and seven of 18 (39%) saliva specimens of donors; geometric mean titers of positive specimens were 10(1.5), 10(1.4), and 10(1.2) tissue culture infectious dose 50/ml (TCID 50/ml), respectively. Rhinovirus was present in 20 of 43 (46%) recipient hand rinses, with a geometric mean titer of 10(1.4)TCID50/ml. Virus on donors' hands was transferred to recipients' fingers during 20 of 28 (71%) 10-second hand-contact exposures. These findings support the concept that hand contact/self-inoculation may be an important natural route of rhinovirus transmission.

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Year:  1978        PMID: 205151     DOI: 10.7326/0003-4819-88-4-463

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN: 0003-4819            Impact factor:   25.391


  82 in total

1.  Improving the health of workers in indoor environments: priority research needs for a national occupational research agenda.

Authors:  Mark J Mendell; William J Fisk; Kathleen Kreiss; Hal Levin; Darryl Alexander; William S Cain; John R Girman; Cynthia J Hines; Paul A Jensen; Donald K Milton; Larry P Rexroat; Kenneth M Wallingford
Journal:  Am J Public Health       Date:  2002-09       Impact factor: 9.308

2.  Impact of non-pharmaceutical interventions on URIs and influenza in crowded, urban households.

Authors:  Elaine L Larson; Yu-hui Ferng; Jennifer Wong-McLoughlin; Shuang Wang; Michael Haber; Stephen S Morse
Journal:  Public Health Rep       Date:  2010 Mar-Apr       Impact factor: 2.792

3.  Banning the Handshake from Healthcare Settings is not the Solution to Poor Hand Hygiene.

Authors:  Herbert L Fred
Journal:  Tex Heart Inst J       Date:  2015-12-01

Review 4.  Significance of fomites in the spread of respiratory and enteric viral disease.

Authors:  Stephanie A Boone; Charles P Gerba
Journal:  Appl Environ Microbiol       Date:  2007-01-12       Impact factor: 4.792

5.  Fabric-skin models to assess infection transfer for impetigo contagiosa in a kindergarten scenario.

Authors:  A Gerhardts; S V Henze; D Bockmühl; D Höfer
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-02-10       Impact factor: 3.267

6.  Transfer efficiency of bacteria and viruses from porous and nonporous fomites to fingers under different relative humidity conditions.

Authors:  Gerardo U Lopez; Charles P Gerba; Akrum H Tamimi; Masaaki Kitajima; Sheri L Maxwell; Joan B Rose
Journal:  Appl Environ Microbiol       Date:  2013-07-12       Impact factor: 4.792

7.  Hand contamination with human rhinovirus in Bangladesh.

Authors:  Stephen P Luby; Xiaoyan Lu; Theresa Cromeans; M A Yushuf Sharker; Mohammad Abdul Kadir; Dean D Erdman
Journal:  J Med Virol       Date:  2014-04-24       Impact factor: 2.327

Review 8.  Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs.

Authors:  Günter Kampf; Axel Kramer
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

9.  An experimental model for study of Candida survival and transmission in human volunteers.

Authors:  M S Rangel-Frausto; A K Houston; M J Bale; C Fu; R P Wenzel
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1994-07       Impact factor: 3.267

10.  An optimized method to detect influenza virus and human rhinovirus from exhaled breath and the airborne environment.

Authors:  Patricia Fabian; James Joseph McDevitt; Wai-Ming Lee; Eugene Andres Houseman; Donald Kirby Milton
Journal:  J Environ Monit       Date:  2008-12-01
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