| Literature DB >> 20514129 |
Jordanka Zlatanova, Jean-Marc Victor.
Abstract
Chromatin structure is a powerful tool to regulate eukaryotic transcription. Moreover, nucleosomes are constantly remodeled, disassembled, and reassembled in the body of transcribed genes. Here we propose a general model that explains, in quantitative terms, how transcription elongation affects nucleosome structure at a distance as a result of the positive torque the polymerases create as they translocate along DNA templates.Year: 2009 PMID: 20514129 PMCID: PMC2839809 DOI: 10.2976/1.3249971
Source DB: PubMed Journal: HFSP J ISSN: 1955-205X