Literature DB >> 20514031

Hepatic AAV gene transfer and the immune system: friends or foes?

Roland W Herzog1.   

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Year:  2010        PMID: 20514031      PMCID: PMC2889731          DOI: 10.1038/mt.2010.96

Source DB:  PubMed          Journal:  Mol Ther        ISSN: 1525-0016            Impact factor:   11.454


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  19 in total

1.  Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer.

Authors:  Ou Cao; Eric Dobrzynski; Lixin Wang; Sushrusha Nayak; Bethany Mingle; Cox Terhorst; Roland W Herzog
Journal:  Blood       Date:  2007-04-16       Impact factor: 22.113

2.  Tolerance in clinical liver transplantation.

Authors:  Raffaello Cortesini
Journal:  Transpl Immunol       Date:  2006-11-13       Impact factor: 1.708

Review 3.  The liver as a lymphoid organ.

Authors:  Ian Nicholas Crispe
Journal:  Annu Rev Immunol       Date:  2009       Impact factor: 28.527

4.  Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy.

Authors:  Glenn P Niemeyer; Roland W Herzog; Jane Mount; Valder R Arruda; D Michael Tillson; John Hathcock; Frederik W van Ginkel; Katherine A High; Clinton D Lothrop
Journal:  Blood       Date:  2008-10-28       Impact factor: 22.113

5.  Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes.

Authors:  Hua Li; Samuel L Murphy; Wynetta Giles-Davis; Shyrie Edmonson; Zhiquan Xiang; Yan Li; Marcio O Lasaro; Katherine A High; Hildegund Cj Ertl
Journal:  Mol Ther       Date:  2007-01-23       Impact factor: 11.454

6.  Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid.

Authors:  Luk H Vandenberghe; Lili Wang; Suryanarayan Somanathan; Yan Zhi; Joanita Figueredo; Roberto Calcedo; Julio Sanmiguel; Ravi A Desai; Christopher S Chen; Julie Johnston; Rebecca L Grant; Guangping Gao; James M Wilson
Journal:  Nat Med       Date:  2006-07-16       Impact factor: 53.440

Review 7.  Hepatic gene transfer as a means of tolerance induction to transgene products.

Authors:  Paul A LoDuca; Brad E Hoffman; Roland W Herzog
Journal:  Curr Gene Ther       Date:  2009-04       Impact factor: 4.391

8.  CD8(+) T-cell responses to adeno-associated virus capsid in humans.

Authors:  Federico Mingozzi; Marcela V Maus; Daniel J Hui; Denise E Sabatino; Samuel L Murphy; John E J Rasko; Margaret V Ragni; Catherine S Manno; Jurg Sommer; Haiyan Jiang; Glenn F Pierce; Hildegund C J Ertl; Katherine A High
Journal:  Nat Med       Date:  2007-03-18       Impact factor: 53.440

9.  Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.

Authors:  Catherine S Manno; Glenn F Pierce; Valder R Arruda; Bertil Glader; Margaret Ragni; John J Rasko; John Rasko; Margareth C Ozelo; Keith Hoots; Philip Blatt; Barbara Konkle; Michael Dake; Robin Kaye; Mahmood Razavi; Albert Zajko; James Zehnder; Pradip K Rustagi; Hiroyuki Nakai; Amy Chew; Debra Leonard; J Fraser Wright; Ruth R Lessard; Jürg M Sommer; Michael Tigges; Denise Sabatino; Alvin Luk; Haiyan Jiang; Federico Mingozzi; Linda Couto; Hildegund C Ertl; Katherine A High; Mark A Kay
Journal:  Nat Med       Date:  2006-02-12       Impact factor: 53.440

10.  Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

Authors:  Federico Mingozzi; Nicole C Hasbrouck; Etiena Basner-Tschakarjan; Shyrie A Edmonson; Daniel J Hui; Denise E Sabatino; Shangzhen Zhou; J Fraser Wright; Haiyan Jiang; Glenn F Pierce; Valder R Arruda; Katherine A High
Journal:  Blood       Date:  2007-07-03       Impact factor: 22.113

View more
  7 in total

1.  Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector.

Authors:  Dawn E Bowles; Scott W J McPhee; Chengwen Li; Steven J Gray; Jade J Samulski; Angelique S Camp; Juan Li; Bing Wang; Paul E Monahan; Joseph E Rabinowitz; Joshua C Grieger; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Xiao Xiao; R Jude Samulski
Journal:  Mol Ther       Date:  2011-11-08       Impact factor: 11.454

2.  The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer.

Authors:  Susan M Faust; Peter Bell; Yanqing Zhu; Julio Sanmiguel; James M Wilson
Journal:  Mol Ther       Date:  2013-10-15       Impact factor: 11.454

3.  Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection.

Authors:  Kelsey R Pflepsen; Cristina D Peterson; Kelley F Kitto; Maureen S Riedl; R Scott McIvor; George L Wilcox; Lucy Vulchanova; Carolyn A Fairbanks
Journal:  Mol Pharm       Date:  2021-08-30       Impact factor: 5.364

4.  Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.

Authors:  David M Markusic; Roland W Herzog
Journal:  J Genet Syndr Gene Ther       Date:  2012-01-18

5.  Genetically reprogrammed, liver-derived insulin-producing cells are glucose-responsive, but susceptible to autoimmune destruction in settings of murine model of type 1 diabetes.

Authors:  Dong-Qi Tang; Lu Shun; Vijay Koya; Yuping Sun; Qiwei Wang; Hai Wang; Shi-Wu Li; Yu Sun; Daniel L Purich; Clare Zhang; Barbara Hansen; Keping Qian; Mark Atkinson; M Ian Phillips; Li-Jun Yang
Journal:  Am J Transl Res       Date:  2013-03-28       Impact factor: 4.060

6.  Integration-deficient lentiviral vectors expressing codon-optimized R338L human FIX restore normal hemostasis in Hemophilia B mice.

Authors:  Thipparat Suwanmanee; Genlin Hu; Tong Gui; Cynthia C Bartholomae; Ina Kutschera; Christof von Kalle; Manfred Schmidt; Paul E Monahan; Tal Kafri
Journal:  Mol Ther       Date:  2013-08-14       Impact factor: 11.454

7.  AAV vector biology in primates: finding the missing link?

Authors:  Roland W Herzog; Andrew M Davidoff; David M Markusic; Amit C Nathwani
Journal:  Mol Ther       Date:  2011-11       Impact factor: 11.454

  7 in total

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