Literature DB >> 20512916

Smurf control in bone cells.

Lianping Xing1, Ming Zhang, Di Chen.   

Abstract

The homologous to the E6-associated protein carboxyl terminus (HECT) domain E3 ubiquitin ligase Smurf1 is the first E3 ligase to be implicated in regulating bone cell function. The involvement of Smurf1 in multiple signaling pathways and pathological conditions is presently an area of extensive scientific interest. This review highlights recent works exploring Smurf-regulated biological processes in bone cells and highlights recent discoveries surrounding the regulatory mechanisms modulating its catalytic activity and substrate recognition capability. Moreover, we discuss the relevance of targeting the HECT E3s through the development of small-molecule inhibitors as an anticancer therapeutic strategy. (c) 2010 Wiley-Liss, Inc.

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Year:  2010        PMID： 20512916      PMCID： PMC2886145          DOI： 10.1002/jcb.22586

Source DB:  PubMed          Journal:  J Cell Biochem        ISSN： 0730-2312            Impact factor:   4.429


  84 in total

1.  Regulation of planar cell polarity by Smurf ubiquitin ligases.

Authors:  Masahiro Narimatsu; Rohit Bose; Melanie Pye; Liang Zhang; Bryan Miller; Peter Ching; Rui Sakuma; Valbona Luga; Luba Roncari; Liliana Attisano; Jeffrey L Wrana
Journal:  Cell       Date:  2009-04-17       Impact factor: 41.582

2.  Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.

Authors:  Qiuqian Wu; Kyung-Ok Kim; Erik R Sampson; Di Chen; Hani Awad; Todd O'Brien; J Edward Puzas; Hicham Drissi; Edward M Schwarz; Regis J O'Keefe; Michael J Zuscik; Randy N Rosier
Journal:  Arthritis Rheum       Date:  2008-10

3.  Mesenchymal stem cells: a future for the treatment of arthritis?

Authors:  Joost Swart; Anton Martens; Nico Wulffraat
Journal:  Joint Bone Spine       Date:  2008-06-16       Impact factor: 4.929

4.  Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins.

Authors:  Ruolin Guo; Motozo Yamashita; Qian Zhang; Quan Zhou; Di Chen; David G Reynolds; Hani A Awad; Laura Yanoso; Lan Zhao; Edward M Schwarz; Ying E Zhang; Brendan F Boyce; Lianping Xing
Journal:  J Biol Chem       Date:  2008-06-19       Impact factor: 5.157

5.  Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2.

Authors:  Peijun P Shi; Xiao R Cao; Eileen M Sweezer; Thomas S Kinney; Nathan R Williams; Russell F Husted; Ramesh Nair; Robert M Weiss; Roger A Williamson; Curt D Sigmund; Peter M Snyder; Olivier Staub; John B Stokes; Baoli Yang
Journal:  Am J Physiol Renal Physiol       Date:  2008-06-04

6.  Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.

Authors:  Erina Fukunaga; Yasumichi Inoue; Setsuro Komiya; Kana Horiguchi; Kouichiro Goto; Masao Saitoh; Keiji Miyazawa; Daizo Koinuma; Aki Hanyu; Takeshi Imamura
Journal:  J Biol Chem       Date:  2008-10-16       Impact factor: 5.157

7.  Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1.

Authors:  Kefeng Lu; Xiushan Yin; Tujun Weng; Shenli Xi; Li Li; Guichun Xing; Xuan Cheng; Xiao Yang; Lingqiang Zhang; Fuchu He
Journal:  Nat Cell Biol       Date:  2008-07-20       Impact factor: 28.824

8.  Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization.

Authors:  Lindolfo da Silva Meirelles; Nance Beyer Nardi
Journal:  Br J Haematol       Date:  2003-11       Impact factor: 6.998

9.  TNF-alpha and IL-1beta inhibit RUNX2 and collagen expression but increase alkaline phosphatase activity and mineralization in human mesenchymal stem cells.

Authors:  J Ding; O Ghali; P Lencel; O Broux; C Chauveau; J C Devedjian; P Hardouin; D Magne
Journal:  Life Sci       Date:  2009-02-03       Impact factor: 5.037

10.  A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome.

Authors:  Alexander G Bassuk; Robyn H Wallace; Aimee Buhr; Andrew R Buller; Zaid Afawi; Masahito Shimojo; Shingo Miyata; Shan Chen; Pedro Gonzalez-Alegre; Hilary L Griesbach; Shu Wu; Marcus Nashelsky; Eszter K Vladar; Dragana Antic; Polly J Ferguson; Sebahattin Cirak; Thomas Voit; Matthew P Scott; Jeffrey D Axelrod; Christina Gurnett; Azhar S Daoud; Sara Kivity; Miriam Y Neufeld; Aziz Mazarib; Rachel Straussberg; Simri Walid; Amos D Korczyn; Diane C Slusarski; Samuel F Berkovic; Hatem I El-Shanti
Journal:  Am J Hum Genet       Date:  2008-10-30       Impact factor: 11.025
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  14 in total

1.  Smurf1 protein negatively regulates interferon-γ signaling through promoting STAT1 protein ubiquitination and degradation.

Authors:  Chao Yuan; Jianni Qi; Xueying Zhao; Chengjiang Gao
Journal:  J Biol Chem       Date:  2012-04-02       Impact factor: 5.157

2.  Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1.

Authors:  Lan Zhao; Jian Huang; Hengwei Zhang; Yi Wang; Lydia E Matesic; Masahiko Takahata; Hani Awad; Di Chen; Lianping Xing
Journal:  Stem Cells       Date:  2011-10       Impact factor: 6.277

3.  Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.

Authors:  Yoshinori Matsumoto; Jose La Rose; Oliver A Kent; Melany J Wagner; Masahiro Narimatsu; Aaron D Levy; Mitchell H Omar; Jiefei Tong; Jonathan R Krieger; Emily Riggs; Yaryna Storozhuk; Julia Pasquale; Manuela Ventura; Behzad Yeganeh; Martin Post; Michael F Moran; Marc D Grynpas; Jeffrey L Wrana; Giulio Superti-Furga; Anthony J Koleske; Ann Marie Pendergast; Robert Rottapel
Journal:  J Clin Invest       Date:  2016-10-31       Impact factor: 14.808

Review 4.  [Functions of non-coding RNAs in the osteogenic differentiation of human periodontal ligament-derived cells].

Authors:  Jia-Hui Wen; Yan-Min Wu; Li-Li Chen
Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi       Date:  2020-06-01

Review 5.  Osteoblast dysfunctions in bone diseases: from cellular and molecular mechanisms to therapeutic strategies.

Authors:  Pierre J Marie
Journal:  Cell Mol Life Sci       Date:  2014-12-09       Impact factor: 9.261

6.  Ubiquitin e3 ligase itch negatively regulates osteoblast differentiation from mesenchymal progenitor cells.

Authors:  Hengwei Zhang; Lianping Xing
Journal:  Stem Cells       Date:  2013-08       Impact factor: 6.277

7.  Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cells.

Authors:  Xiangchun Wang; Chaoyang Jin; Yi Tang; Liu-Ya Tang; Ying E Zhang
Journal:  J Biol Chem       Date:  2013-06-11       Impact factor: 5.157

8.  Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration.

Authors:  Lei Shu; Hengwei Zhang; Brendan F Boyce; Lianping Xing
Journal:  J Bone Miner Res       Date:  2013-09       Impact factor: 6.741

9.  NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation.

Authors:  Jia Chang; Fei Liu; Min Lee; Benjamin Wu; Kang Ting; Janette N Zara; Chia Soo; Khalid Al Hezaimi; Weiping Zou; Xiaohong Chen; David J Mooney; Cun-Yu Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2013-05-20       Impact factor: 11.205

10.  Image-based genome-wide siRNA screen identifies selective autophagy factors.

Authors:  Anthony Orvedahl; Rhea Sumpter; Guanghua Xiao; Aylwin Ng; Zhongju Zou; Yi Tang; Masahiro Narimatsu; Christopher Gilpin; Qihua Sun; Michael Roth; Christian V Forst; Jeffrey L Wrana; Ying E Zhang; Katherine Luby-Phelps; Ramnik J Xavier; Yang Xie; Beth Levine
Journal:  Nature       Date:  2011-12-01       Impact factor: 49.962
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