Literature DB >> 32573144

[Functions of non-coding RNAs in the osteogenic differentiation of human periodontal ligament-derived cells].

Jia-Hui Wen1, Yan-Min Wu1, Li-Li Chen1.   

Abstract

Human periodontal ligament-derived cells serve as an important source of seeding cells in periodontal regenerative medicine, and their osteogenic potential is closely related to alveolar bone repair and periodontal regeneration. Non-coding RNA (ncRNA), such as microRNA, long non-coding RNA, and circular RNA, play important roles in the regu-lation of osteogenic genes in human periodontal ligament-derived cells. In this review, we summarize the target genes, path-ways, and functions of the ncRNA network during osteogenic differentiation of periodontal ligament-derived cells.

Entities:  

Keywords:  circular RNA; long non-coding RNA; microRNA; osteogenic differentiation; periodontal ligament cell; periodontal liga­ment stem cell

Mesh：

Substances：

Year:  2020        PMID： 32573144      PMCID： PMC7296371          DOI： 10.7518/hxkq.2020.03.018

Source DB:  PubMed          Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi        ISSN： 1000-1182


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