PURPOSE: Radiation-induced olfactory neuroblastoma (ONB) is an uncommon neoplasm that is generally associated with a poor prognosis. We describe a new case of olfactory neuroblastoma in a patient previously treated for astrocytoma with holocranial radiotherapy 9 years ago. MATERIALS AND METHODS: We reviewed the medical records of four patients with radiation-induced olfactory neuroblastoma between 2001 and 2009. RESULTS: This work supports the idea that ONB can be induced by radiation. CONCLUSIONS: As radiotherapy is a standard treatment in other tumors, clinicians must be aware of the possibility of a second tumor induced by radiation.
PURPOSE: Radiation-induced olfactory neuroblastoma (ONB) is an uncommon neoplasm that is generally associated with a poor prognosis. We describe a new case of olfactory neuroblastoma in a patient previously treated for astrocytoma with holocranial radiotherapy 9 years ago. MATERIALS AND METHODS: We reviewed the medical records of four patients with radiation-induced olfactory neuroblastoma between 2001 and 2009. RESULTS: This work supports the idea that ONB can be induced by radiation. CONCLUSIONS: As radiotherapy is a standard treatment in other tumors, clinicians must be aware of the possibility of a second tumor induced by radiation.
Authors: C Leclercq; N Penel; J Grosjean; C Fournier; M-O Vilain; D Pasquier; L Ceugnart; L Vanseymortier Journal: Rev Med Interne Date: 2004-12 Impact factor: 0.728